Ÿ International Course in Bioscience and Biotechnology Program Tokyo Institute of Technology

 

Graduate School of Bioscience & Biotechnology

Dept. of Life Science

Dept. of Biological Sciences

Dept. of Biological Information

Dept. of Bioengineering

Dept. of Biomolecular Engineering

 

Integrated doctoral program (3 - 5 yrs)

The Graduate School of Bioscience and Biotechnology has launched a new program entitled gInternational Course in Bioscience and Biotechnologyh within our Integrated Doctoral Education Program. The primary aim of the course is to foster student excellence within our various and sophisticated educational programs by exposing students to the advanced science and technology that underpins medical and environmental industries and to other related areas of bioscience and biotechnology. By enhanced exchange between international and Japanese students, we will produce high level researchers and engineers who will flourish as national and global leaders.

 

Course Program

The program will commence in October of each year, and student education will be conducted in English.

 

1)   A student must be certified at masterfs degree level while attending the course, which will be of at least 3 years duration.

2)   A student must acquire more than 30 credits in the special and general subjects listed below. (exclusive of colloquium (IGC Seminar I – X) and internship credits.) *See the tables below.

3)   A student must acquire more than 4 credits of Bio-Internship. Bio-Internship: a 3-6 month project at research institutes or corporations in Japan. *compulsory

4)   A student must acquire 2 credits of Directed Collaborative Work. *compulsory

5)   A student must take all of the required colloquium (IGC Seminar I – X of each department) credits.

6)   A student usually files for a masterfs degree after acquiring 30 credits in general and special subjects together with one IGC Seminar in each semester (usually a total 2-4 credits). She/he then submits a research report which must be passed according to the examination rules in each department. Students who are admitted to obtain a masterfs degree must take the qualifying examination for the doctoral course immediately, and those who pass it will become students of the doctoral course.

7)   To graduate, doctoral students must present satisfactory mid-term progress reports, and then pass doctoral thesis review and a final oral examination.

 

Standard Courses

1st year

2nd year

3rd year

4th year

M1

M2

D1

D2

 

QP

QP

FP, FE

M1

D1

D2

D3

QP

QP

QP

FP, FE

<Classes>

<Internship>

 

<Researches>

 

QP: qualifying presentation, FP: final presentation, FE: final examination

 


Classes in this list given in English

Class Name

Credit

Lecturer(s)

Semester

Remarks

Advanced Bioengineering

2-0-0

Hirota et al.

Autumn

E, C

Advanced Bioorganic Chemistry

2-0-0

Sekine et al.

Autumn

E, C

Advanced Molecular Biology

2-0-0

Ishikawa et al.

Autumn

E, C

Advanced Life Science Frontiers

2-0-0

 

Spring

E, C

Advanced Course of Molecular Developmental Biology

2-0-0

Tanaka

Autumn

E

Synthesis of Bioactive Substances

2-0-0

Yuasa

Autumn

E

Advanced Cell Biochemistry

2-0-0

Komada

Spring

E

Bio-Nanomechanics

2-0-0

 

Spring

E

Genome-based Drug Discovery

2-0-0

Ishikawa

Spring

E

Advanced Biochemistry

2-0-0

Kitamura et al.

Autumn

O, C

Advanced Biology

2-0-0

Motokawa et al.

Autumn

O, C

Advanced Biophysical Chemistry

2-0-0

Inoue et al.

Autumn

O, C

Advanced Biotechnology Frontiers

2-0-0

 

Spring

O, C

Advanced Course of Biological Recognition and Signaling II

2-0-0

Saito

Autumn

O

Asymmetric Synthesis

2-0-0

Kobayashi

Autumn

O

Advanced Course of Biological Molecular Function

2-0-0

Aizawa

Spring

O

Advanced Developmental Genetics

2-0-0

Kawakami

Spring

O

Structure and Function of Biological Supramolecules

2-0-0

Arisaka

Spring

O

Bioscience and Biotechnology Topics 1 (200X)

1-0-0

Mihara et al.

Spring

C

Bioscience and Biotechnology Topics 2 (200X)

1-0-0

Ichinose et al.

Autumn

C

Advanced Course of Bioscience Communication

2-0-0

Arimura

Autumn

 

Cell Signaling and Regulation

1-0-0

Hirose, Maturana

Autumn

C

Development and Disease

1-0-0

Kitamura, Takeuchi

Autumn

C

Computational Biochemistry@

1-0-0

Sakurai, Harano

Autumn

C

Bionanotechnology

1-0-0

Mihara, Heddle

Autumn

C

gEh or gOh in the remarks column shows that those classes are open in even or odd year, respectively. 

The classes without such symbols are open every year.

gCh in the remarks column indicates the class is common to all departments.

*Must take more than 4 credits in other departments.

 

Internship, Advanced Experiments and Colloquiums (Seminar) of each department (compulsory)

Class Name

Credit

Lecturer(s)

Semester

Remarks

œ@Bio-Internship I

0-4-0

Mentor

Spring

 

œ@Bio-Internship II

0-4-0

Mentor

Autumn

 

Directed Collaborative Work

2-0-0

Mihara, Kajiwara

Autumn

MC 1st year

Advanced Experiments I (each dept)

0-0-2

Mentor

Spring

MC 1st year

Advanced Experiments II (each dept)

0-0-2

Mentor

Autumn

MC 1st year

IGC Seminar I (each dept)

1

Mentor

Autumn

MC 1st year

IGC Seminar II (each dept)

1

Mentor

Spring

MC 1st year

IGC Seminar III (each dept)

1

Mentor

Autumn

MC 2nd year

IGC Seminar IV (each dept)

1

Mentor

Spring

MC 2nd year

IGC Seminar V (each dept)

1

Mentor

Autumn

DC 1st year

IGC Seminar VI (each dept)

1

Mentor

Spring

DC 1st year

IGC Seminar VII (each dept)

1

Mentor

Autumn

DC 2nd year

IGC Seminar VIII (each dept)

1

Mentor

Spring

DC 2nd year

IGC Seminar IX (each dept)

1

Mentor

Autumn

DC 3rd year

IGC Seminar X (each dept)

1

Mentor

Spring

DC 3rd year

œ Taking one of these credits is compulsory.@@›@Compulsory

 

 

Tokyo Tech Common Lectures

Class Name

Credit

Lecturer(s)

Semester

Remarks

Japanese 1 First-b

0-2-0

Marutani

Autumn

 

Japanese 1 Second-b

0-2-0

Marutani

Spring

Suzukakedai

Japanese 2 First-b

0-2-0

Marutani

Autumn

Suzukakedai

Japanese 2 Second-b

0-2-0

Marutani

Spring

Suzukakedai

Japanese 3S-b

0-2-0

Moriizumi

Autumn

Suzukakedai

Japanese 3S-b

0-2-0

Moriizumi

Spring

Suzukakedai

Japanese 4S-b

0-2-0

Moriizumi

Autumn

Suzukakedai

Japanese 4S-b

0-2-0

Moriizumi

Spring

Suzukakedai

Japanese 5LS

0-2-0

Marutani

Autumn/Spring

O-okayama

Japanese 5WR

0-2-0

Yoshizawa

Autumn/Spring

O-okayama

Japanese 6LS

0-2-0

Marutani

Autumn/Spring

O-okayama

Japanese 6WR

0-2-0

Kaseda

Autumn/Spring

O-okayama

Advanced Oral Expression in English CIIa

0-2-0

Abel

Autumn

 

Advanced Oral Expression in English CIIb

0-2-0

Pulvers

Autumn

 

Advanced Oral Expression in English CIIc

0-2-0

Morton

Autumn

 

Advanced Oral Expression in English CIId

0-2-0

Kiyama

Autumn

 

Academic Presentation in English CIIc

0-2-0

Gildart

Autumn

 

 

Advanced Bioorganic Chemistry (2-0-0)

Autumn semester of even year

Prof. Junji HIROTA, Prof. Satoshi NAKAMURA and Assoc. Prof. Tomoko MATSUDA

 

(Aim)

Most advanced research status of bioengineering is to be learned, where bio-functions derived from biological elements such as viruses/phages, enzymes, microbes, plant/animal cells are applied to the construction of innovative systems for producing materials and/or energy, and contributing environmental technology.

 

(Schedule)

1.    Mechanism and application of biocatalysis

     1-1 Kinetics of biocatalytic reactions

     1-2 Mechanism of biocatalytic reactions

      1-3 Production of useful materials with biocatalysts

      1-4 Pront of industrial production with biocatalysts

2.   Molecular bioengineering of extremozymes and related proteins

      2-1 Methodology for effcient foreign gene expression

       2-2 Extremophiles and extremozymes

       2-3 Protein engineering of extremozymes and related proteins

       2-4 Directed evolution of extremozymes and related proteins

3.   Biotransformation for organic synthesis

       3-1 Kinetic resolution using hydrolytic enzymes (I)

       3-2 Kinetic resolution using hydrolytic enzymes (II)

       3-3 Reduction and oxidation

       3-4 Future directions in biotransformation

 

 

Advanced Bioorganic Chemistry (2-0-0)

Autumn semester of even year     

Prof. Mituo SEKINE, Assoc. Prof. Hideya YUASA, and Assoc. Prof. Kohji SEIO

 

(Aim)

In addition to analyze bioorganic molecules and/or organic molecules, their synthesis is a next critical step to take advantage of these molecules in a more positive way.  Actually, derivatives of these molecules, which are solely obtained by the artificial synthesis, often prove much more useful than the original biomolecules.  In this lecture, such an essential field of organic chemistry, i.e., how to construct and design our own biomolecules, will be discussed.

 

(Schedule)

  1.  Introduction, what are molecular recognitions?

  2.  Molecular recognition of enzymes (1)

  3.  Molecular recognition of enzymes (2)

  4.  Molecular recognition of enzymes (3)

  5.  Synthesis and design of small biomolecules (1)

  6.  Synthesis and design of small biomolecules (2)

  7.  New trends in organic synthesis (1)

  8.  New trends in organic synthesis (2)

  9.  New trends in organic synthesis (3)

 10.  New trends in organic synthesis (4)

 11.  Synthesis of classical prostaglandins

 12.  Synthesis of new prostaglandins and other cyclopentanoids

 

(How to Grade)

Attendance and reports (and possibly examination?)

 

(Text, etc.)

Necessary stuff for this class will be provided by the lecturers.

 

 

Advanced Molecular Biology (2-0-0)

Autumn semester of even year         

 

Prof. Toshihisa ISHIKAWA Prof. Makio TOKUNAGA and Associate Prof. Susumu KAJIWARA

 

 

 

(Aim)

The lecture series consists of three academic/research fields which will be presented by the above-mentioned three professors of the Graduate Course of Bioscience and Biotechnology.  Each of the fields contains recent hot topics: i.e., Modern Molecular Genomics, Molecular Imaging Technology, and Essential Molecular Biology of Microorganisms.  The lecture will be provided in English (no Japanese!) and open to all students belonging to both the International Graduate Course and the regular Graduate Course.

 

(Contents of Lectures)

(1) Introduction to Advanced Molecular Biology and Explanation of the Course.

 

I.      Modern Molecular Genomics (Prof. T. Ishikawa)

(2) Genetic Diversity of ABC Transporters: From Bacteria to Human.

(3) Human ABC Transporters: Structure and Function.

(4) Pharmacogeomics and Clinical Applications.

(5) Personalized Medicine in Cancer Chemotherapy.

 

II.    Molecular Imaging Technology (Prof. Makio Tokunaga)

(6) Introduction to Molecular Imaging and Microscopy.

(7) Fluorescence Microscopy and Fluorescent Probes.

(8) Molecular Imaging.

(9) Topics on Molecular Imaging.

 

III.   Essential Molecular Biology of Microorganisms (Associate Prof. S. Kajiwara)

(10) Introduction to Microorganisms and Microbiology.

(11) Basic Understanding of Microbe Physiology.

(12) Gene Expression of Microorganisms.

(13) Introduction to Pathogenic Fungi.

 

(How to Grade)

Attendance and reports

 

 

Advanced Course of Molecular Developmental Biology (2-0-0)

Autumn semester of odd year

Assoc. Prof. Mikiko TANAKA

 

(Aim)

This course is designed to provide a basic understanding of the cellular and molecular mechanisms that regulate vertebrate development.

 

(Schedule)

1.  Introduction to Developmental Biology

2.  Nervous System

3.  Neural Crest Cells

4.  Heart

5.  Paraxial and Intermediate mesoderm

6.  Endoderm

7.  Limb Development

8.  Blood Vessels and Blood Cells

9.  Germ Line

10.  Regeneration

11.  Medical Implications

 

(How to Grade)

Attendance and presentation

 

 

Synthesis of Bioactive Substances (2-0-0)

Autumn semester of even year

Assoc. Prof. Hideya YUASA

 

(Aim)

Organic synthesis is one of the most powerful tools to create drugs for diseases, such as cancer, diabetes, flu, and etc. Thus the knowledge and skills of organic synthesis are prerequisite for the research in pharmaceutical industry. The aim of this class is to have you understand the logics and mechanisms underlying the design and synthesis of bioactive molecules. To make the class less bored, each lecture will deal with the synthesis of a few compounds, with which the basic principles behind the constituent reactions will be uncovered. Therefore, you do not have to attend all of the classes. The first half of this class will be based on the text book, gTop Drugs: Top Synthetic Routesh (John Saunders, Oxford University Press: Oxford, 2000). Our own research results are discussed in the latter half.

 

(Schedule)

1.  Inhibitors of angiotensin converting enzyme

2.  Blockade of angiotensin-II receptors

3.  Calcium channel blockers

4.  Antagonists of histamine receptors

5.  Proton pump inhibitors

6.  Modulation of central serotonin

7.  Ligands for benzodiazepine receptor

8.  Blockers of the H1 recptor

9.  Inhibitors of HIV reverse transcriptase

10.  Anti-bacterial DNA gyrase inhibitors

11.  Glycosidase inhibitors against diabetes

12.  Carbohydrate-based future drugs

13.  Principles of mimics and mimetics

14.  Dynamic molecules for future drugs

15.  Peptide synthesis (optional)

 

(How to grade)

Attendance and report

 

 

 

Advanced Cell Biochemistry (2-0-0)

Spring semester of even year

Assoc. Prof. Masayuki KOMADA

(Aim)

Precise transport of proteins to their destinations in the cell is essential for various cellular functions.  Membrane traffic is a major protein transport process between organelles made of lipid membranes.  This course focuses on the molecular mechanisms as well as physiological and pathological roles of various membrane traffic processes in eukaryotic cells.  Equal efforts will be made to address the fundamentals and recent findings on each subject.

 

(Schedule)

1.  Endocytosis

2.  Traffic from endosomes to lysosomes

3.  Budding of viruses from host cells

4.  Traffic between the endoplasmic reticulum (ER) and Golgi

5.  Exocytosis

6.  Traffic from the Golgi to endosomes

7.  Rab family of small GTPases

8.  Autophagy

9.  Kinesin-mediated vesicle transport

10.  Mechanisms of membrane protein localization

 

(How to Grade)

Tests, report

 

 

Genome-based Drug Discovery

Spring semester of even year

Prof. Toshihisa ISHIKAWA

 

(Aim)

In the 21st century, emerging genomic science and technologies are shifting the paradigm of drug discovery research and improving the strategy of medical care for patients.  In order to realize the personalized medicine, it is critically important to understand molecular mechanisms underlying inter-individual differences in the drug response, namely, pharmacological effect vs. side effect.  Pharmacogenomics, the study of influence of genetic factors on drug action, is increasingly important for predicting pharmacokinetics profiles and/or adverse reactions of drugs.

In this lecture series, basic science underlying the genome-based drug discovery and current critical issues will be presented and mutually discussed.

 

(Schedule)

1.  Introduction: History of drug discovery research (lecture)

 2.  Genome-based drug discovery (lecture)

 3.  Target validation and high throughput screening (lecture)

 4.  Presentation and free discussion

 5.  Medicinal chemistry (lecture)

6.  Presentation and free discussion

 7.  Pharmacology and toxicology (lecture)

 8.  Presentation and free discussion

 9.  Pharmacogenomics (lecture)

10.  Presentation and free discussion

11.  Recent topics (lecture)

12.  Business strategies of pharmaceutical companies (lecture)

13.  Presentation and free discussion

 

(How to grade)

Graduate students are expected to attend lectures and to actively participate in discussion.  Following lectures, graduate students will be requested to present their own reports on particular subjects, such as target validation and high throughput screening, medicinal chemistry, pharmacology and toxicology, pharmacogenomics, and business strategies of pharmaceutical companies.  Lecture, presentation, and discussion will be provided in English only (no Japanese!). 

 

(Text)

"Pharmacogenomics" (Eds.: W. Kalow, U.A. Meyer, R.F. Tyndale) Marcel Dekker, Inc. New York/Basel.

 

Advanced Biochemistry (2-0-0)

Autumn semester of odd years

Prof. Naomi KITAMURA, Assoc. Prof. Fumio ARISAKA, and Assoc. Prof. Yoichi TAGAWA

 

This course will be given in English. Major areas of contemporary biochemistry will be covered to help understand the chemical basis of life.The themes include (1) biological membranes, chemical communication between cells, and intracellular trafficking; (2) protein motifs, protein folds, and macromolecular assembly; and (3) extracellular matrices and biochemistry of cell community.

 

(Schedule)

Prof. KITAMURA:  Biological membranes

1.   Proteins, lipids, and biological membranes

2.   Localization and targeting of proteins

3.   Signaling molecules

4.   Receptors, second messengers, and intracellular signaling molecules

 

Prof. ARISAKA:  Protein structure and assembly

1.   Protein structure and motif

2.   Protein folding

3.   Protein-protein interactions

4.   Macromolecular assembly

 

Prof. TAGAWA:  Biochemistry of cell community

1.   Cell surface chemistry

2.   Cell-matrix interactions

3.   Cell-cell interactions

4.   Cellular engineering and tissue engineering

 

Advanced Biology (2-0-0)

Autumn semester of odd year

Prof. Norihiro OKADA, Assoc. Prof. Atsushi KAWAKAMI and Assoc. Prof. Masaki KAJIKAWA

This course will be given in English. Major areas of contemporary biology will cover to help understand the modern biology. The themes include (1) Evolutional science, (2) Developmental biology, and (3) Mobile element science.

 

(Aim)

The evolution of genes, genomes and organisms will be studied (N. Okada).

Cellular and molecular mechanisms that regulate animal development will be studied. Main focus will be on principles for establishment of the body plan and formation of selected organs (A. Kawakami).

Transposable elements and their impact on the eukaryotic genome evolution will be studied (M. Kajikawa). 

 

(Schedule)

1.  Natural selection (Okada)

2.  Neutral theory (Okada)

3.  Genetic drift (Okada)

4.  Phylogenetic analysis (Okada)

5.  Development and organ formation in vertebrates (Kawakami)

6.  Patterning embryo (Kawakami)

7.  Genetics and signaling (Kawakami)

8.  Organ regeneration I (Kawakami)

9.  Organ regeneration II (Kawakami)

10.  The structure and mobilization mechanism of transposon (Kajikawa)

11.  The structure and mobilization mechanism of retroposon (Kajikawa)

12.  The impact of transposable elements on the genome evolution (Kajikawa)

 

 

Advanced Biophysical Chemistry (2-0-0)

Autumn semester of odd year

This course is given by Prof. Yoshio INOUE, Assoc. Prof. Toshiya OSADA and Prof. Minoru SAKURAI.

 

Lectures will be given along gPhysical Chemistry, Principles and Applications in Biological Sciencesh 4th Edition,

by I. Tinoco, K. Sauer, J. C. Wang, and J. D. Puglisi, Prentice-Hall, Inc., (2002).

 

(Schedule)

1.   Introduction (Yoshio Inoue)

2.   The First Law: Energy Is Conserved

3.   The Second Law: The Entropy of the Universe Increases

4.   The Free Energy and Chemical Equilibria (Toshiya Osada)

5.   Free Energy and Physical Equilibria

6.   Molecular Structures and Interactions: Theory (Minoru Sakurai)

 

 

Advanced Course of Biological Recognition and Signaling II (2-0-0)

Autumn Semester of odd year

Assoc. Prof. Yuji SAITO

 

(Aim)

Students will learn the up-to-date knowledge and the ways to carry out research about biological signal transduction. This object could be attained not only from the lectures given by the instructor but also by actively participating in a series of presentations given by fellow students.

 

(Schedule)

1.  Give basic and general understanding about Biological Signal Transduction. (2 weeks)

Explain various receptors and molecules involved in different biological signal transduction pathways, and cross-talks among them.

2.  Discuss about various oncogenes and tumor suppressors with regard to apoptosis, differentiation and cancer,

based on topics published in recent literatures. (2 weeks)

3.  Students are expected to make a bit formal presentations about a series of subjects chosen from current literature.

Students will learn from this experience how to write and read papers as well as how to give a talk in conferences. (8 weeks)

 

(How to grade)

Students are expected to attend lectures as often as possible, and actively participate in the discussion about the topics presented by fellow students.

 

 

Asymmetric Synthesis (2-0-0)

Autumn semester of odd year

Assoc. Prof. Yuichi KOBAYASHI

 

(Aim)

Asymmetric reaction is a powerful method to obtain enantiomerically enriched compounds for synthesis of biologically important compounds.  Among the efficient asymmetric reactions so far published, several types of reactions listed below will be described.  The principle for the creation of stereocenter(s) are discussed.  

 

(Schedule)

 1.  Fundamental Aspects of Asymmetric Synthesis

2.   Preparation of Enantiomerically Enriched Compounds by means of Optical Resolution, Asymmetric@Synthesis,Chiral Pool Method, Reactions using Enzymes

 3.  Diastereoselection and Enantioselection

 4.  Enolate Formation and Asymmetric Alkylation

 5.  Asymmetric Aldol Reaction: Part 1

 6.  Asymmetric Aldol Reaction: Part 2

 7.  Catalytic Asymmetric Reactions: Part 1: Hydrogenation, Isomerization, Allylic Substitution

 8.  Catalytic Asymmetric Reactions: Part 2: Cyclopropanation, Diels-Alder Reaction 

 9.  Asymmetric Epoxidation

10.  Transformations of Epoxides

11.  Asymmetric Dihydroxylation  

12.  Dissymmetrization of Compounds with Symmetry Elements

13.  Chiral Pool Method

14.  Asymmetric Synthesis of Biologically Active Compounds

15.  Summary

 

(How to grade)

Attendance and report

 

 

Advanced Course of Biological Molecular Function (2-0-0)

Spring semester of odd year

Associate Prof. Yasunori AIZAWA

 

(Course Description)

This course considers the structural and functional aspects of the most fundamental cellular molecules, ribonucleic acids (RNAs).  Topics in this course covers mechanisms on expression, processing, intracellular transport, and functional outcome of different classes of protein-coding RNAs as well as noncoding RNAs (ribosomal RNAs, transfer RNAs, small RNAs, and polyadenylated noncoding RNAs).  In addition, to deeply understand these RNA-related mechanisms, this course provides additional topics on genome structures and functions.  The technique and logic used to address important issues in RNA biology is also emphasized.  Lectures cover the broad topic areas and class discussions focus on representative papers in the field. 

 

(Topics)

1.   Genome Architecture and Function

2.   Definition of Gene and Complexity of Mammalian Genomes

3.   RNA Expression and Processing

4.   Intracellular RNA Transport

5.   Gene Regulation through RNAs

6.   Noncoding RNA

 

(Student requirements)

Intensive reading assigned papers and high quality performance in the class discussion is required from all the students.   

 

 

Advanced Developmental Genetics (2-0-0)

Spring semester of odd year

Assoc. Prof. Atsushi KAWAKAMI

 

(Aim)

Cellular and molecular mechanisms that regulate animal development, organ formation and related issues will be studied. Through the studies of developmental genetics and related areas, students will develop ability for oral presentation in English about respective researches and/or issues related to developmental genetics. Final goal of this class is to cultivate a faculty for logical thinking and scientific communication.

 

(Schedule)

1.   Introduction, schedules etc.

2.   Developmental genetics in model animal, particularly in small fish species

3.   Cellular and molecular background of tissue regeneration

4-12.  Presentations by students

 

(How to Grade)

Attendance and presentation

 

(Text, etc.)

Not required

 

 

Structure and Function of Biological Supramolecules (2-0-0)

Spring semester of odd year

Assoc. Professor Fumio ARISAKA

 

(Aim)

Among biological supramolecules, focus will be made on the protein supramolecules and the mechanisms and principles that control the molecular assembly and the methods of analyses will be taught. First, hierarchical structure of proteins will be introduced and varieties of interactions involved in the formation of protein supramolecules will be explained. After describing the various structures in the cell, structure of viruses will be introduced and the mechanism of assembly and the structural changes during assembly and infection process will be described through examples of bacteriophages along with the methodology of the analyses.

 

(Schedule)

1.       Overview of supramolecules in the cell

      |tight complex and association-dissociation system|

2.  Hierarchical structure of proteins

3.  Protein-protein interactions

4.  Repeats and symmetry in protein supramolecules

5.  Co-operativity in the structure formation of protein assembly

6.  Structure of viruses

7.  Principle of quasi-equivalence

      |CasparEKlug theory|

8.  Methods of analyses on assemblyFapplication of conditional lethal mutants and in vivo and in vitro

        complementation

9.  Methods of strucutre determinationFelectron microscopy, X-ray crystallography etc.

10.   Mehtods of analysis in protein-protein interactionsFanaytical ultracentrifugation, surface plasmon resonance, isothermal titration microcalorimetry, light scattering

11.  paper review (1)

12.  paper review (2)

13.  paper review (3)

14.  Summary

 

(How to Grade)

Attendance to the lectures and reports

 

 

Cell signaling and regulation(1-0-0)  

Autumn semester

Assistant Prof. Andres MATURANA

(Aim)

Communication between cells is essential in order to maintain an organism alive and functional. Extracellular signals (such as hormones, neurotransmitter, osmotic changesc) are transduced specifically into the intracellular space to generate an appropriate answer from the cell. These lectures will focuses on the molecular mechanisms of transmission of the intracellular signaling.  

 

(Schedule)

1.   Introduction to cell signaling.

2.   Receptors.

3.   Kinase and Phosphatase.

4.   Localization of the signal: Scaffolding proteins

5.   Calcium signaling

6.   Ion channels part I

7.   Ion channels part II 

 

(How to Grade)

Attendance and report 

 

 

Development and Diseases(1-0-0)

Autumn semester

Assistant Prof. Jun K. TAKEUCHI

 

(Aim)

This field of science is defined to know gus-human beingh, that means how we are established and born, how we are different from other people or animals, and how diseases are occurred.  Since genes for making body pattern was first reported, many indispensable genes for patterning and diseases have been identified and characterized for over twenty years. And such gene-profiling study will be finished soon, following the genome projects.  Next, we need to know combinatorial functions of genes to explain how complicated human body is formed and why significance of disease differs among people.  In this lecture, exciting and outstanding studies will be picked up in each term, and will be discussed why it was gexciting and outstandingg.  We will focus on anatomical, genetic & developmental, and technical approaches to study embryology and aging.

 

(Schedule)

1.   Anatomical Science

2.   Early Development

3.   Late Development

4.   Heart Development

5.   Diseases

6.   Functional Analyses & ES Technologies

7.   Evolutional Sciences & Future Effort

 

(How to Guide)

Successful guidance for this lecture has at least two important requirements.  First, a couple of interesting papers will be picked up and discussed as an introduction at every class.  From this project, students will figure out new insights or important points about the theme of each term.  Second, every class follows these papers to understand their background and their thought.  Through lecture, students will have the opportunity to meet the ideas of great scientists who have made significant contributions in their field and our life. 

 

(Text)

Developmental Biology 8th edition (S.Gilbert)

Heart 2nd edition (N.Rosenthial & R.Harvey)

 

 

Computational Biochemistry(1-0-0)

Autumn semester

Assistant Prof. Yuichi HARANO

 

(Aim)

Computational methods on biochemistry are overviewed. Various topics on molecular biology are introduced in the class. The methods are based on quantum chemistry, classical mechanics, statistical mechanics, and thermodynamics. How computational methods can contribute to biological science will be discussed, and the idea on theoretical biochemistry will be mastered. The basic knowledge on physical chemistry is required.

 

(Schedule)

1.   Introduction; how does the computer contribute to biochemistry?

2.   Quantum mechanical methods.

3.   Molecular dynamics simulation of biomolecules (1).

4.   Molecular dynamics simulation of biomolecules (2).

5.   Thermodynamics on biochemistry.

6.   Solution chemistry on biomolecules.

7.   Bioinformatics on structural biology.

 

(How to Grade)

Attendance and reports.

 

(Text, etc.)

Necessary stuff for this class will be provided by the lecturers.

 

 

Bionanotechnology(1-0-0)

Autumn semester

Assistant Prof. Jonathan HEDDLE

 

(Aim)

Using biological molecules to construct functional materials at the nanoscale for uses as diverse as microelectronics and therapeutics is a new and exciting field. The aim of this lecture series is to introduce the ideas and concepts behind bionanotechnology, giving examples from recent research.

 

(Schedule)

What is Bionanotechnology?  An Introduction

1.   Current Uses of Bionanotechnology

2.   Bionanotechnology with protein spheres

3.   Bionanotechnology with TRAP protein part I

4.   Bionanotechnology with TRAP protein part II

5.   DNA as a bionanotechnology tool

6.   Future prospects of Bionanotechnology

 

(How to Grade)

Attendance and Report

 

 

List of Regular-course Lectures

(Given in Japanese, but international graduate course students can also attend and earn credits)

 

Department of Life Science

Class

Credit

Lecturer

Semester

Note

Bio-intern Ship I

0-0-2

Mihara et al.

Spring

C

Bio-intern Ship II

0-0-2

Yuasa et al.

Autumn

C

Bioinformatics

2-0-0

Tabata et al.

Spring

C

Industrial Sociology

2-0-0

Kudo et al.

Spring

C

Brain Science

2-0-0

Matsui et al.

Spring

C

Biotechnical Reading

2-0-0

Shibata

Spring

C

Biotechnical Writing

2-0-0

Roger Prior

Spring

C

Synthesis of Bioactive Substances

2-0-0

Yuasa

Autumn

E

Advanced Course of Molecular Structure Analysis

2-0-0

Spring

E

Advanced Structural Biology

2-0-0

Autumn

O

Advanced Course of Biochemical Genetics

2-0-0

Shishido

Spring

E

Advanced Course of Molecular Reguration

2-0-0

Kajiwara

Spring

O

Organic Chemistry of Biomolecules

2-0-0

Sekine

Autumn

E

Molecular Recognition of Biomolecules

2-0-0

Seio

Spring

O

Advanced Course of Biological Physics

2-0-0

@

Spring

E

Bio-Nanomechanics

2-0-0

@

Spring

E

Advanced Course of Medical Chemistry

2-0-0

Ichinose

Autumn

O

Advanced Molecular Life Science

2-0-0

Muto

Spring

E

Science of Radiation and Beams

2-0-0

Ogawa

Spring

Instrumental Analysis

2-0-0

Naruke

Spring

Biochemistry

2-0-0

Yoshida

Autumn

Advanced Course of Bioscience Communication

2-0-0

Arimura

Autumn

Chemistry of the oxygen atmosphere

1-0-0

Maruyama, et al.

Autumn

Science of Photosynthetic Organisms

1-0-0

Maruyama, Ohta

Spring

History of life and modern life under extreme environments

1-0-0

Maruyama, Takai

Spring

Project Managing Skills I

2-0-0

Kadota

Spring

Project Managing Skills IV

2-0-0

Furuta

Autumn

Lecture on Advanced Life Science 1

1-0-0

@

Spring

O

Lecture on Advanced Life Science 2

1-0-0

@

Spring

E

Lecture on Advanced Life Science 3

1-0-0

@

Spring

O

Lecture on Advanced Life Science 4

1-0-0

@

Spring

E

Directed Laboratory Works in Life Science 1

0-0-2

@

Spring

Master's Course ‡@

Directed Laboratory Works in Life Science 2

0-0-2

@

Autumn

Master's Course ‡@

Seminar in Life Science 1

1

@

Spring

Master's Course ‡@

Seminar in Life Science 2

1

@

Autumn

Master's Course ‡@

Seminar in Life Science 3

1

@

Spring

Master's Course ‡A

Seminar in Life Science 4

1

@

Autumn

Master's Course ‡A

Seminar in Life Science 5

1

@

Spring

Doctoral Course ‡@

Seminar in Life Science 6

1

@

Autumn

Doctoral Course ‡@

Seminar in Life Science 7

1

@

Spring

Doctoral Course ‡A

Seminar in Life Science 8

1

@

Autumn

Doctoral Course ‡A

Seminar in Life Science 9

1

@

Spring

Doctoral Course ‡B

Seminar in Life Science 10

1

@

Autumn

Doctoral Course ‡B

Advanced Bioscience

2-0-0

Gu, Kajiwara

Spring

Tsinghua University

Advanced Biotechnology

2-0-0

Xing, Kobatake

Spring

Tsinghua University

Advanced Bio-molecule Science

2-0-0

Wang, Komada

Spring

Tsinghua University

Advanced Life Science (Integrated Doctoral Education Program)

2-0-0

Sekine

Autumn

@

Advanced Biologic Sciences (Integrated Doctoral Education Program)

2-0-0

Komada

Spring

@

Advanced Biological Information (Integrated Doctoral Education Program)

2-0-0

Handa

Autumn

@

Advanced Bioengineering (Integrated Doctoral Education Program)

2-0-0

Mihara

Autumn

@

Advanced Biomolecular Engineering (Integrated Doctoral Education Program)

2-0-0

Fujihira

Spring

@

 

1) The classes with › symbols should be passed in the indicated academic years. ‡@, ‡A, ‡B in

the remarks column indicate academic years.

2) gEh or gOh symbols in the remarks column show that those classes are opened in even or odd

years, respectively. The classes without such symbols are opened every year.

 

Department of Biological Sciences

Class

Credit

Lecturer

Semester

Note

Bio-intern Ship I

0-0-2

Mihra et al.

Spring

C

Bio-intern Ship II

0-0-2

Yuasa et al.

Spring

C

Bioinformatics

2-0-0

Tabata et al.

Spring

C

Industrial Sociology

2-0-0

Kudo et al.

Spring

C

Brain Science

2-0-0

Matsui et al.

Spring

C

Biotechnical Reading

2-0-0

Shibata

Spring

C

Biotechnical Writing

2-0-0

Roger Prior

Spring

C

Advanced Course of Biological Substances

2-0-0

Kitamura

Spring

O

Advanced Cell Biochemistry

2-0-0

Komada

Spring

E

Advanced Course of Biological Recognition and Signalling I

2-0-0

Hirose

Spring

E

Advanced Course of Biological Recognition and Signalling II

2-0-0

Saito

Autumn

O

Choromosome Architecture & Dynamics

2-0-0

Shirahige

Spring

O

Advanced Course of Molecular Developmental  Biology

2-0-0

Tanaka

Autumn

E

Advanced Course of Molecular Evolution

2-0-0

Okada

Spring

O

Genetic Informatics

2-0-0

Kajikawa

Spring

E

Photobioenergetics

2-0-0

Takamiya

Spring

E

Advanced Course of Morphogenesis

2-0-0

Ohta

Autumn

O

Advanced Functional Morphology

2-0-0

Motokawa

Spring

O

Advanced Course of Ecology

2-0-0

Kohshima

Autumn

E

Molecular Biology

2-0-0

Sakaki, et al.

Spring

O

Sciences of Radiation and Beams

2-0-0

Ogawa, et al.

Spring

Advanced Course of Bioscience Communication

2-0-0

Arimura

Autumn

Chemistry of the oxygen atmosphere

1-0-0

Maruyama, et al.

Autumn

@

Science of Photosynthetic Organisms

1-0-0

Maruyama, Ohta

Spring

@

History of life and modern life under extreme environments

1-0-0

Maruyama ,Takai

Spring

Advanced Course in Biosystem I

1-0-0

@

Spring

O

Advanced Course in Biosystem II

1-0-0

@

Spring

E

Advanced Course in Biosystem III

1-0-0

@

Autumn

O

Advanced Course in Biosystem IV

1-0-0

@

Spring

E

› Advanced Experiments of Biosystem I

0-0-2

Mentor

Spring

Master's Course ‡@

› Advanced Experiments of Biosystem II

0-0-2

Mentor

Autumn

Master's Course ‡@

› Seminar in Biosystem I

1

Mentor

Spring

Master's Course ‡@

› Seminar in Biosystem II

1

Mentor

Autumn

Master's Course ‡@

› Seminar in Biosystem III

1

Mentor

Spring

Master's Course ‡A

› Seminar in Biosystem IV

1

Mentor

Autumn

Master's Course ‡A

› Seminar in Biosystem V

1

Mentor

Spring

Doctoral Course ‡@

› Seminar in Biosystem VI

1

Mentor

Autumn

Doctoral Course ‡@

› Seminar in Biosystem VII

1

Mentor

Spring

Doctoral Course ‡A

› Seminar in Biosystem VIII

1

Mentor

Autumn

Doctoral Course ‡A

› Seminar in Biosystem IX

1

Mentor

Spring

Doctoral Course ‡B

› Seminar in Biosystem X

1

Mentor

Autumn

Doctoral Course ‡B

Advanced Bioscience

2-0-0

Gu, Kajiwara

Spring

Tsinghua University

Advanced Biotechnology

2-0-0

Xing, Kobatake

Spring

Tsinghua University

Advanced Bio-molecule Science

2-0-0

Wang, Komada

Spring

Tsinghua University

Advanced Life Science (Integrated Doctoral Education Program)

2-0-0

Sekine

Autumn

Advanced Biologic Sciences (Integrated Doctoral Education Program)

2-0-0

Komada

Spring

Advanced Biological Information (Integrated Doctoral Education Program)

2-0-0

Handa

Autumn

Advanced Bioengineering (Integrated Doctoral Education Program)

2-0-0

Mihara

Autumn

Advanced Biomolecular Engineering (Integrated Doctoral Education Program)

2-0-0

Fujihira

Spring


1) The classes with › symbols should be passed in the indicated academic years. ‡@, ‡A, ‡B in

the remarks column indicate academic years.

2) gEh or gOh symbols in the remarks column show that those classes are opened in even or odd years,

respectively. The classes without such symbols are opened every year.

 

Department of Biological Information

Class

Credit

Lecturer

Semester

Note

Bio-intern Ship I

0-0-2

Mihara et al.

Spring

C

Bio-intern Ship II

0-0-2

Yuasa et al.

Autumn

C

Bioinformatics

2-0-0

Tabata et al.

Spring

C

Industrial Sociology

2-0-0

Kudo et al.

Spring

C

Brain Science

2-0-0

Matsui et al.

Spring

C

Biotechnical Reading

2-0-0

Shibata

Spring

C

Biotechnical Writing

2-0-0

Roger Prior

Spring

C

Advanced Molecular Cell Biology I

2-0-0

Kishimoto

Autumn

E

Advanced Molecular Cell Biology II

2-0-0

Ohsumi

Autumn

O

Medical Engineering of Biorecognition

2-0-0

Handa

Spring

E

Molecular Immunology and Bone Biology

2-0-0

Kudo

Spring

E

Introduction to genome information science

2-0-0

Kurokawa

Autumn

E

Information Biotechnology

2-0-0

Kobatake

Spring

O

Organic Chemistry for Life Science

2-0-0

Hosoya

Spring

E

Molecular Imaging

2-0-0

Tokunaga

Spring

O

Advanced Cell and Molecular Biology II

2-0-0

Ochiya

Spring

O

Advanced Course of Bioscience Communication

2-0-0

Arimura

Autumn

Chemistry of the oxygen atmosphere

1-0-0

Maruyama, et al.

Autumn

Science of Photosynthetic Organisms

1-0-0

Maruyama, Ohta

Spring

History of life and modern life under extreme environments

1-0-0

Maruyama ,Takai

Spring

Project Managing Skills I

2-0-0

Kadota

Spring

Project Managing Skills IV

2-0-0

Furuta

Autumn

Advanced Course In Biological Information I

1-0-0

Spring

O

Advanced Course In Biological Information II

1-0-0

@

Spring

E

Advanced Course In Biological Information III

1-0-0

Autumn

O

Advanced Course In Biological Information IV

1-0-0

@

Autumn

E

Advanced Experiments of Biological Information I

0-0-2

@

Spring

Master's Course ‡@

Advanced Experiments of Biological Information II

0-0-2

@

Autumn

Master's Course ‡@

Seminars in Biological Information I

1

@

Spring

Master's Course ‡@

Seminars in Biological Information II

1

@

Autumn

Master's Course ‡@

Seminars in Biological Information III

1

@

Spring

Master's Course ‡A

Seminars in Biological Information IV

1

@

Autumn

Master's Course ‡A

Seminars in Biological Information V

1

@

Spring

Doctoral Course ‡@

Seminars in Biological Information VI

1

@

Autumn

Doctoral Course ‡@

Seminars in Biological Information VII

1

@

Spring

Doctoral Course ‡A

Seminars in Biological Information VIII

1

@

Autumn

Doctoral Course ‡A

Seminars in Biological Information VIIII

1

@

Spring

Doctoral Course ‡B

Seminars in Biological Information X

1

@

Autumn

Doctoral Course ‡B

Advanced Bioscience

2-0-0

Gu, Kajiwara

Spring

Tsinghua University

Advanced Biotechnology

2-0-0

Xing, Kobatake

Spring

Tsinghua University

Advanced Bio-molecule Science

2-0-0

Wang, Komada

Spring

Tsinghua University

Advanced Life Science (Integrated Doctoral Education Program)

2-0-0

Sekine

Autumn

Advanced Biologic Sciences (Integrated Doctoral Education Program)

2-0-0

Komada

Spring

Advanced Biological Information (Integrated Doctoral Education Program)

2-0-0

Handa

Autumn

Advanced Bioengineering (Integrated Doctoral Education Program)

2-0-0

Mihara

Autumn

Advanced Biomolecular Engineering (Integrated Doctoral Education Program)

2-0-0

Fujihira

Spring


1) The classes with symbols should be passed in the indicated academic years. ‡@, ‡A, ‡B in

the remarks column indicate academic years.

2) gEh or gOh symbols in the remarks column show that those classes are opened in even or odd years,

respectively. The classes without such symbols are opened every year.

 

Department of Bioengineering

Class

Credit

Lecturer

Semester

Note

Bio-intern Ship I

0-0-2

Mihara et al.

Spring

C

Bio-intern Ship II

0-0-2

Yuasa et al.

Autumn

C

Bioinformatics

2-0-0

Tabata et al.

Spring

C

Industrial Sociology

2-0-0

Kudo et al.

Spring

C

Brain Science

2-0-0

Matsui et al.

Spring

C

Biotechnical Reading

2-0-0

Shibata

Spring

C

Biotechnical Writing

2-0-0

Roger Prior

Spring

C

Advanced Biochemical Process

2-0-0

Kitazume

Autumn

O

Advanced Course of Biocatalysis

2-0-0

Matsuda

Spring

E

Advanced Course of Biopolymers

2-0-0

Mihara

Autumn

E

Advanced Course of Cell Physiology

2-0-0

Hamaguchi

Spring

E

Advanced Biofunctional Engineering

2-0-0

Asakura

Autumn

E

Advanced Biochemical Engineering

2-0-0

Tanji

Spring

E

Now and Future of Environmental Biotechnology

2-0-0

@

Spring

Molecular Bioengineering

2-0-0

Fukui

Spring

O

Advanced Protein Engineering

2-0-0

Nakamura

Autumn

E

Advanced Course of Cell Technology

2-0-0

Wachi

Autumn

O

Reaction Kinetics

2-0-0

@

Autumn

O

Science of Radiation and Beams

2-0-0

Ko‚ˆno, et al.

Spring

COE Earth Program :Special Colloquium 1

1-1-0

@

Spring

COE Earth Program :Special Colloquium 2

1-1-0

@

Autumn

COE Earth Program :Special Colloquium 3

1-1-0

@

Spring

COE Earth Program :Special Colloquium 4

1-1-0

@

Autumn

COE Earth Program :Special Colloquium 5

1-1-0

@

Spring

COE Earth Program :Special Colloquium 6

1-1-0

@

Autumn

Chemistry of the oxygen atmosphere

1-0-0

Maruyama, et al.

Autumn

Science of Photosynthetic Organisms

1-0-0

Maruyama ,Ohta

Spring

History of life and modern life under extreme environments

1-0-0

Maruyama ,Takai

Spring

Project Managing Skills ‡T

2-0-0

Kadota

Spring

Project Managing Skills ‡W

2-0-0

Furuta

Autumn

Advanced Course in Bioengineering I

1-0-0

@

Spring

O

Advanced Course in Bioengineering II

1-0-0

@

Spring

E

Advanced Course in Bioengineering III

1-0-0

@

Autumn

O

Advanced Course in Bioengineering IV

1-0-0

@

Autumn

E

Advanced Experiments of Bioscience and Biotechnology I

0-0-2

@

Spring

Master's Course ‡@

Advanced Experiments of Bioscience and Biotechnology II

0-0-2

@

Autumn

Master's Course ‡@

Seminar in Bioengineering I

1

@

Spring

Master's Course ‡@

Seminar in Bioengineering II

1

@

Autumn

Master's Course ‡@

Seminar in Bioengineering III

1

@

Spring

Master's Course ‡A

Seminar in Bioengineering IV

1

@

Autumn

Master's Course ‡A

Seminar in Bioengineering V

1

@

Spring

Doctoral Course ‡@

Seminar in Bioengineering VI

1

@

Autumn

Doctoral Course ‡@

Seminar in Bioengineering VII

1

@

Spring

Doctoral Course ‡A

Seminar in Bioengineering VIII

1

@

Autumn

Doctoral Course ‡A

Seminar in Bioengineering IX

1

@

Spring

Doctoral Course ‡B

Seminar in Bioengineering X

1

@

Autumn

Doctoral Course ‡B

Advanced Bioscience

2-0-0

Gu, Kajiwara

Spring

Tsinghua University

Advanced Biotechnology

2-0-0

Xing, Kobatake

Spring

Tsinghua University

Advanced Bio-molecule Science

2-0-0

Wang, Komada

Spring

Tsinghua University

Advanced Life Science (Integrated Doctoral Education Program)

2-0-0

Sekine

Autumn

Advanced Biologic Sciences (Integrated Doctoral Education Program)

2-0-0

Komada

Spring

Advanced Biological Information (Integrated Doctoral Education Program)

2-0-0

Handa

Autumn

Advanced Bioengineering (Integrated Doctoral Education Program)

2-0-0

Mihara

Autumn

Advanced Biomolecular Engineering (Integrated Doctoral Education Program)

2-0-0

Fujihira

Spring

 

1) The classes with symbols should be passed in the indicated academic years. ‡@, ‡A, ‡B in

the remarks column indicate academic years.

2) gEh or gOh symbols in the remarks column show that those classes are opened in even or odd years,

respectively. The classes without such symbols are opened every year.

 

Department of Biomolecular Engineering

Class

Credit

Lecturer

Semester

Note

Bio-intern Ship I

0-0-2

Mihra et al.

Spring

C

Bio-intern Ship II

0-0-2

Yuasa et al.

Spring

C

Bioinformatics

2-0-0

Tabata et al.

Spring

C

Industrial Sociology

2-0-0

Kudo et al.

Spring

C

Brain Science

2-0-0

Matsui et al.

Spring

C

Biotechnical Reading

2-0-0

Shibata

Spring

C

Biotechnical Writing

2-0-0

Roger Prior

Spring

C

Measurement of Biomolecules

2-0-0

Fujihira

Spring

E

Advanced Physical Chemistry of Biomolecules

2-0-0

Inoue et al.

Autumn

E

Biological Computational Chemistry

2-0-0

Sakurai

Spring

O

Biophysical Chemistry

2-0-0

Ohtani

Spring

O

Biomimetic Chemistry

2-0-0

Okahata, Mori

Spring

O

Artificial Bioorganic Chemistry

2-0-0

Mori, Okahata

Spring

E

Advanced Biofunctional Materials

2-0-0

Akaike

Autumn

E

Biofunctional Molecule Design

2-0-0

Tagawa et al.

Spring

O

Genome-based Drug Discovery

2-0-0

Ishikawa

Spring

E

Molecular Design of Biological Importance

2-0-0

Urabe

Spring

E

Asymmetric Synthesis

2-0-0

Kobayashi

Autumn

O

Chemistry of the oxygen atmosphere

1-0-0

Maruyama at el.

Autumn

History of life and modern life under extreme environments

1-0-0

Maruyama, Kohshima

Spring

History of life and modern life under extreme environments

1-0-0

Maruyama ,Takai

Spring

Project Managing Skills I

2-0-0

Kadota

Spring

Project Managing Skills III

2-0-0

Furuta

Autumn

Advanced Course in Biomolecular Engineering I

1-0-0

@

Spring

O

Advanced Course in Biomolecular Engineering II

1-0-0

@

Spring

E

Advanced Course in Biomolecular Engineering III

1-0-0

@

Autumn

O

Advanced Course in Biomolecular Engineering IV

1-0-0

@

Autumn

E

Advanced Experiments of Bioscience and Biotechnology I

0-0-2

@

Spring

Master's Course ‡@

Advanced Experiments of Bioscience and Biotechnology II

0-0-2

@

Autumn

Master's Course ‡@

Seminar in Biomolecular Engineering I

1

@

Spring

Master's Course ‡@

Seminar in Biomolecular Engineering II

1

@

Autumn

Master's Course ‡@

Seminar in Biomolecular Engineering III

1

@

Spring

Master's Course ‡A

Seminar in Biomolecular Engineering IV

1

@

Autumn

Master's Course ‡A

Seminar in Biomolecular Engineering V

1

@

Spring

Doctoral Course ‡@

Seminar in Biomolecular Engineering VI

1

@

Autumn

Doctoral Course ‡@

Seminar in Biomolecular Engineering VII

1

@

Spring

Doctoral Course ‡A

Seminar in Biomolecular Engineering VIII

1

@

Autumn

Doctoral Course ‡A

Seminar in Biomolecular Engineering VIIII

1

@

Spring

Doctoral Course ‡B

Seminar in Biomolecular Engineering X

1

@

Autumn

Doctoral Course ‡B

Advanced Bioscience

2-0-0

Gu, Kajiwara

Spring

Tsinghua University

Advanced Biotechnology

2-0-0

Xing, Kobatake

Spring

Tsinghua University

Advanced Bio-molecule Science

2-0-0

Wang, Komada

Spring

Tsinghua University

Advanced Life Science (Integrated Doctoral Education Program)

2-0-0

Sekine

Autumn

Advanced Biologic Sciences (Integrated Doctoral Education Program)

2-0-0

Komada

Spring

Advanced Biological Information (Integrated Doctoral Education Program)

2-0-0

Handa

Autumn

Advanced Bioengineering (Integrated Doctoral Education Program)

2-0-0

Mihara

Autumn

Advanced Biomolecular Engineering (Integrated Doctoral Education Program)

2-0-0

Fujihira

Spring


1) The classes with symbols should be passed in the indicated academic years. ‡@, ‡A, ‡B in

the remarks column indicate academic years.

2) gEh or gOh symbols in the remarks column show that those classes are opened in even or odd years,

respectively. The classes without such symbols are opened every year.