♦ International Course in Bioscience and Biotechnology Program Tokyo Institute of Technology

1. Program Outline

Integrated doctoral program (3 - 5 yrs)
The Graduate School of Bioscience and Biotechnology has launched a new program entitled “International Course in Bioscience and Biotechnology” within our Integrated Doctoral Education Program. The primary aim of the course is to foster student excellence within our various and sophisticated educational programs by exposing students to the advanced science and technology that underpins medical and environmental industries and to other related areas of bioscience and biotechnology. By enhanced exchange between international and Japanese students, we will produce high level researchers and engineers who will flourish as national and global leaders.

2. Faculty

Graduate School of Bioscience & Biotechnology
Dept. of Life Science
Dept. of Biological Sciences
Dept. of Biological Information
Dept. of Bioengineering
Dept. of Biomolecular Engineering

3. Guide to Study in IGC Course Program

The program will commence in October of each year, and student education will be conducted in English.

1)   A student must be certified at master’s degree level while attending the course, which will be of at least 3 years duration.

2)   A student must acquire more than 25 credits in the special and general subjects listed below. (exclusive of colloquium (IGC Seminar I – X) and internship (IGC Bio-Internship I, II) credits.) *See the tables below.

3)   In these subjects, a student must acquire 2 credits of Directed Collaboration Works. *compulsory

4)   A student must acquire more than 4 credits of IGC Bio-Internship. IGC Bio-Internship: a 3-6 month project at research institutes or corporations in Japan. *compulsory

5)   A student must take all of the required colloquium (IGC Seminar I – X of each department) credits. *compulsory

6)   A student usually files for a master’s degree after acquiring 30 credits in general and special subjects together with one IGC Seminar in each semester (usually a total 2-4 credits). She/he then submits a research report which must be passed according to the examination rules in each department. Students who are admitted to obtain a master’s degree must take the qualifying examination for the doctoral course immediately, and those who pass it will become students of the doctoral course.

7)   To graduate, doctoral students must present satisfactory mid-term progress reports, and then pass doctoral thesis review and a final oral examination.

4. Tables of Course Subjects

Classes in this list given in English
Subject	Registration Number	Credit	Chair	Semester	Remarks (See footnotes)
Bioengineering Now	78023	2-0-0	Nakamura et al.	Autumn	E, C
Advanced Bioorganic Chemistry	78014	2-0-0	Urabe et al.	Autumn	E, C
Advanced Molecular Biology	78015	2-0-0	Kudo et al.	Autumn	E, C
Advanced Life Science Frontiers	78025	2-0-0		Spring	E, C
Advanced Course of Molecular Developmental Biology	81006	2-0-0	Tanaka	Autumn	E
Advanced Cell Biochemistry	81002	2-0-0	Komada	Spring	E
Advanced Biochemistry	78021	2-0-0	Akaike et al.	Autumn	O, C
Advanced Biology	78022	2-0-0	Ohta et al.	Autumn	O, C
Advanced Biophysical Chemistry	78013	2-0-0	Murakami et al.	Autumn	O, C
Advanced Biotechnology Frontiers	78024	2-0-0		Spring	O, C
Molecular Recognition of Biomolecules	78008	2-0-0	Seio et al.	Autumn	O
Advanced Course of Biological Recognition and Signaling II	81004	2-0-0	Nakamura et al.	Autumn	O
Advanced Life Science and Nanomedicine	79009	2-0-0	Kondoh	Spring	E
Asymmetric Synthesis	79011	2-0-0	Kobayashi	Autumn	O
Advanced Course of Biological Molecular Function	78001	2-0-0	Aizawa	Spring	O
Advanced Developmental Genetics	72006	2-0-0	Kawakami	Spring	O
Structure and Function of Biological Supramolecules	78103	2-0-0	Arisaka	Spring	O
Advanced Course of Bioorganic Engineering	82003	2-0-0	Mihara, Matsuda	Autumn	E
Bioscience and Biotechnology Topics 2 (2011)	78099	1-0-0	Yuasa et al.	Autumn	C
Evaluation in International Perspective	78083	2-0-0	Sato	Autumn	C
Advanced Course of Bioscience Communication	81014	2-0-0	Arimura	Autumn
Presentation Skill for Science and Technology	78090	2-0-0	Martin Meldrum	Spring
“E” or “O” in the remarks column shows that those classes are open in even or odd year, respectively. The classes without such symbols are open every year. “C” in the remarks column indicates the class is common to all departments. *Must take more than 4 credits in other departments.
Internship, Directed Laboratory Works and Colloquiums (Seminar) of each department (compulsory)
Subject	Registration Number	Credit	Chair	Semester	Remarks (See footnotes)
IGC Bio-Internship I	78091	0-4-0	Kajiwara et al.	Autumn
IGC Bio-Internship II	78092	0-4-0	Kajiwara et al.	Spring
Directed Collaboration Works	78071	2-0-0	Kajiwara, Mihara	Autumn	MC 1st year
Directed Laboratory Works I (each dept)		0-0-2	Mentor	Spring	MC 1st year
Directed Laboratory Works II (each dept)		0-0-2	Mentor	Autumn	MC 1st year
IGC Seminar I (each dept)		1	Mentor	Autumn	MC 1st year
IGC Seminar II (each dept)		1	Mentor	Spring	MC 1st year
IGC Seminar III (each dept)		1	Mentor	Autumn	MC 2nd year
IGC Seminar IV (each dept)		1	Mentor	Spring	MC 2nd year
IGC Seminar V (each dept)		1	Mentor	Autumn	DC 1st year
IGC Seminar VI (each dept)		1	Mentor	Spring	DC 1st year
IGC Seminar VII (each dept)		1	Mentor	Autumn	DC 2nd year
IGC Seminar VIII (each dept)		1	Mentor	Spring	DC 2nd year
IGC Seminar IX (each dept)		1	Mentor	Autumn	DC 3rd year
IGC Seminar X (each dept)		1	Mentor	Spring	DC 3rd year
Taking one of these credits is compulsory. Compulsory
Tokyo Tech Common Lectures
Subject	Registration Number	Credit	Chair	Semester	Remarks (See footnotes)
Japanese 1 First	99601	0-2-0	Marutani	Autumn
Japanese 1 Second	99602	0-2-0	Marutani	Spring	S
Japanese 2 First	99603	0-2-0	Marutani	Autumn	S
Japanese 2 Second	99604	0-2-0	Marutani	Spring	S
Japanese 3S-Autumn	99607	0-2-0	Moriizumi	Autumn	S
Japanese 3S-Spring	99605	0-2-0	Moriizumi	Spring	S
Japanese 4S-Autumn	99611	0-2-0	Moriizumi	Autumn	S
Japanese 4S-Spring	99609	0-2-0	Moriizumi	Spring	S
Japanese 5LS	99615	0-2-0	Marutani	Autumn/Spring	O
Japanese 5WR	99616	0-2-0	Yoshizawa	Autumn/Spring	O
Japanese 6LS	99619	0-2-0	Marutani	Autumn/Spring	O
Japanese 6WR	99620	0-2-0	Kaseda	Autumn/Spring	O
Advanced Oral Expression in English CIIa	99082	0-2-0	Abel	Autumn
Advanced Oral Expression in English CIIb	99086	0-2-0	Pulvers	Autumn
Advanced Oral Expression in English CIIc	99088	0-2-0	Morton	Autumn
Advanced Oral Expression in English CIId	99090	0-2-0	Kiyama	Autumn
Academic Presentation in English CIIc	99126	0-2-0	Gildart	Autumn
“S” or “O” in the remarks column shows that those classes are open at Suzukakedai campus or O-okayama campus

5. Syllabus of Course Subjects

78023
Bioengineering Now
Autumn Semester (2-0-0) (Even Years)
Prof. Satoshi NAKAMURA, Prof. Hisakazu MIHARA and Assoc. Prof. Toshiaki FUKUI

(Aim)
Most advanced research status of bioengineering is to be learned, where bio-functions derived from biological elements such as viruses/phages, enzymes, microbes, plant/animal cells are applied to the construction of innovative systems for producing materials and/or energy, and contributing environmental technology.

78014
Advanced Bioorganic Chemistry
Autumn Semester (2-0-0) (Even Years)
Prof. Hirokazu URABE, Prof. Yuichi KOBAYASHI and Assoc. Prof. Toshiaki MORI

(Aim)
Bioorganic chemistry related to “Bio activity” as well as advanced organic chemistry necessary for the study of Bioscience and biotechnology is expounded.

78015
Advanced Molecular Biology
Autumn Semester (2-0-0) (Even Years)
Prof. Akira KUDO, Prof. Hiroshi IWASAKI and Prof. Takehiko ITOH

This course will feature the molecular biological aspects of a variety of biological phenomena, such as embryogenesis, cell differentiation, signal transduction, transcriptional regulation, cell response, etc. In addition, future aspects of gene technology, genetic diagnosis, and therapy will be presented. This course will be made in English.

78025
Advanced Life Science Frontiers
Spring Semester (2-0-0) (Even Years)

81006
Advanced Course of Molecular Developmental Biology
Autumn Semester (2-0-0) (Even Years)
Assoc. Prof. Mikiko TANAKA

(Aim)
This course is designed to provide a basic understanding of the cellular and molecular mechanisms that regulate vertebrate development.

(Schedule)

1. Introduction to Developmental Biology
2. Nervous System
3. Neural Crest Cells
4. Heart
5. Paraxial and Intermediate mesoderm
6. Endoderm
7. Limb Development
8. Blood Vessels and Blood Cells
9. Germ Line
10. Regeneration
11. Medical Implications

(How to Grade)
Attendance and presentation

81002
Advanced Cell Biochemistry
Spring Semester (2-0-0) (Even Years)
Assoc. Prof. Masayuki KOMADA

(Aim)
Each intracellular organelle contains specific proteins to fulfill its own function. Therefore, precise transport of proteins to destined organelles is essential for cellular functions. This course focuses on molecular mechanisms of various protein transport processes within eukaryotic cells, in relation to the functions of organelles involved. Physiological and pathological roles of the transport processes will also be a major focus of this course. Equal efforts will be made to address the fundamentals and recent findings on each subject.

(Schedule)

1. Overview of organelles and intracellular protein transport
2. Transport from cytoplasm to nucleus
3. Transport from cytoplasm to mitochondria
4. Endocytosis (transport from plasma membrane to endosome)
5. Transport from endosome to lysosome
6. Transport from from Golgi to endosome
7. Transport from endoplasmic reticulum (ER) to Golgi
8. Exocytosis (transport from Golgi to plasma membrane)
9. Autophagy (transport from cytoplasm to lysosome)

(How to Grade)
Small tests in the last ~15 min of each class and a term report

78021
Advanced Biochemistry
Autumn Semester (2-0-0) (Odd Years)
Prof. Toshihiro AKAIKE, Assoc. Prof. Masayuki KOMADA, and Assoc.Prof. Kazunori TACHIBANA

Major areas of contemporary biochemistry will be covered to help understand the chemical basis of life. The themes include (1) biological membranes, chemical communication between cells, and intracellular trafficking; (2) protein motifs, protein folds, and macromolecular assembly; and (3) extracellular matrices and biochemistry of cell community.

(Schedule)
Prof. AKAIKE, Assoc.Prof. TACHIBANA : Biochemistry of Cell Community

1. Cell Surface Chemistry
2. Cell-matrix interactions
3. Cell-Cell Interactions
4. Applications to Cellular Engineering and Regenerative medicine
5. Applications to Drug and gene Delivery

Assoc. Prof. KOMADA : Signaling from growth factor receptors

1. Overview of the growth factor-receptor system
2. Signaling from tyrosine kinase-type receptors
3. Signaling from (1) serine/threonine kinase-type receptors and (2) receptors without kinase activity
4. Downregulation of growth factor receptors

78022
Advanced Biology
Autumn Semester (2-0-0) (Odd Years)
Prof. Hiroyuki OHTA, Prof. Yukihisa HAMAGUCHI and Assoc. Prof. Mikiko TANAKA.

This course will be given in English. Major areas of contemporary biology will be covered to help understand the modern biology

78013
Advanced Biophysical Chemistry
Autumn Semester (2-0-0) (Odd Years)
Prof. Satoshi MURAKAMI , Assoc. Prof. Nobuhiro HAYASHI and Assoc. Prof. Yuki YAMAGUCHI

This lecture will be given in English, Topics on advanced biophysical chemistry will be stated with the principles of the basic analytical instruments for the biological material.

78024
Advanced Biophysical Chemistry
Spring Semester (2-0-0) (Odd Years)

78008
Molecular Recognition of Biomolecules
Autumn Semester (2-0-0) (Odd Years)
Assoc. Prof. Koji SEIO, Prof. Hideya YUASA

(Aim)
Molecular recognition plays quite important roles in the biological processes such as gene expressions, enzymatic reactions, ligand-receptor interactions and cell-cell interactions. In this lecture, the molecular recognitions involving DNA, RNA, drugs, carbohydrates and peptides are discussed from the view points of organic chemistry and physical chemistry.

(Schedule)

1. Principles of molecular recognition (1)
2. Principles of molecular recognition (2)
3. Thermodynamics of molecular recognition
4. Structure of nucleic acids
5. Molecular recognition of nucleic acids (1)
6. Molecular recognition of nucleic acids (2)
7. Recognition of DNA by small molecules
8. Structure and function of carbohydrates
9. Molecular recognition of carbohydrates and related compounds (1)
10. Molecular recognition of carbohydrates and related compounds (2)
11. Molecular recognition of clinically important drugs (1)
12. Molecular recognition of clinically important drugs (2)
13. Principles of mimics and mimetics
14. Dynamic molecules for future drugs
15. Peptide synthesis (optional)

81004
Advanced Course of Biological Recognition and Signaling II
Autumn Semester (2-0-0) (Odd Years)
Assoc. Prof. Nobuhiro NAKAMURA, Assoc. Prof. Junji YAMAUCHI, Assoc. Prof. Toru HIROTA

(Aim)
Students will learn the up-to-date knowledge and the ways to carry out research about biological signal transduction. This object could be attained not only from the lectures given by the instructor but also by actively participating in a series of presentations given by fellow students.

(Schedule)

1. Give basic and general understanding about Biological Signal Transduction. (2 weeks)
   Explain various receptors and molecules involved in different biological signal transduction pathways, and cross-talks among them.
2. Discuss about various oncogenes and tumor suppressors with regard to apoptosis, differentiation and cancer, based on topics published in recent literatures. (2 weeks)
3. Students are expected to make a bit formal presentations about a series of subjects chosen from current literature.
   Students will learn from this experience how to write and read papers as well as how to give a talk in conferences. (8 weeks)
4. Regulation of functions and morphology of mitochondria.

(How to grade)
Students are expected to attend lectures and quizzes as often as possible, and actively participate in the discussion about the topics presented by fellow students.

79009
Advanced Life Science and Nanomedicine
Spring Semester (2-0-0) (Even Years)
Prof. Shinae KONDOH

It aims to obtain the rudimentary knowledge of life sciences, and to understand the latest studies related to an advanced medical treatment that applies nanotechnology, the cellular engineering, molecular biology, and the genetic engineering.

79011
Asymmetric Synthesis
Autumn Semester (2-0-0) (Odd Years)
Prof. Yuichi KOBAYASHI

(Aim)
Asymmetric reaction is a powerful method to obtain enantiomerically enriched compounds for synthesis of biologically important compounds. Among the efficient asymmetric reactions so far published, several types of reactions listed below will be described. The principle for the creation of stereocenter is discussed.

(Schedule)

1. Fundamental Aspects of Asymmetric Synthesis
2. Preparation of Enantiomerically Enriched Compounds by means of Optical Resolution, Asymmetric Synthesis, Chiral Pool Method, Reactions using Enzymes
3. Diastereoselection and Enantioselection
4. Enolate Formation and Asymmetric Alkylation
5. Asymmetric Aldol Reaction: Part 1
6. Asymmetric Aldol Reaction: Part 2
7. Catalytic Asymmetric Reactions: Part 1: Hydrogenation, Isomerization, Allylic Substitution
8. Catalytic Asymmetric Reactions: Part 2: Cyclopropanation, Diels-Alder Reaction
9. Asymmetric Epoxidation
10. Transformations of Epoxides
11. Asymmetric Dihydroxylation
12. Dissymmetrization of Compounds with Symmetry Elements
13. Chiral Pool Method
14. Asymmetric Synthesis of Biologically Active Compounds
15. Summary

(How to grade)
Attendance and report

78001
Advanced Course of Biological Molecular Function
Spring Semester (2-0-0) (Odd Years)
Assoc. Prof. Yasunori AIZAWA

(Course Description)
This course considers the structural and functional aspects of the most fundamental cellular molecules, ribonucleic acids (RNAs). Topics in this course covers mechanisms on expression, processing, intracellular transport, and functional outcome of different classes of protein-coding RNAs as well as noncoding RNAs (ribosomal RNAs, transfer RNAs, small RNAs, and polyadenylated noncoding RNAs). In addition, to deeply understand these RNA-related mechanisms, this course provides additional topics on genome structures and functions. The technique and logic used to address important issues in RNA biology is also emphasized. Lectures cover the broad topic areas and class discussions focus on representative papers in the field.

(Topics)

1. Genome Architecture and Function
2. Definition of Gene and Complexity of Mammalian Genomes
3. RNA Expression and Processing
4. Intracellular RNA Transport
5. Gene Regulation through RNAs
6. Noncoding RNA

(Student requirements)
Intensive reading assigned papers and high quality performance in the class discussion is required from all the students.

72006
Advanced Developmental Genetics
Spring Semester (2-0-0) (Odd Years)
Assoc. Prof. Atsushi KAWAKAMI

(Aim)
Cellular and molecular mechanisms that regulate animal development, organ formation and related issues will be studied. Through the studies of developmental genetics and related areas, students will develop ability for oral presentation in English about respective researches and/or issues related to developmental genetics. Final goal of this class is to cultivate a faculty for logical thinking and scientific communication.

(Schedule)

1. 1.  Introduction, schedules etc.
2. 2.  Developmental genetics in model animal, particularly in small fish species
3. 3.  Cellular and molecular background of tissue regeneration
4. 4-12.  Presentations by students

(How to Grade)
Attendance and presentation

78103
Structure and Function of Biological Supramolecules
Spring Semester (2-0-0) (Odd Years)
Prof. Fumio ARISAKA

(Aim)
Among biological supramolecules, focus will be made on the protein supramolecules and the mechanisms and principles that control the molecular assembly and the methods of analyses will be taught. First, hierarchical structure of proteins will be introduced and varieties of interactions involved in the formation of protein supramolecules will be explained. After describing the various structures in the cell, structure of viruses will be introduced and the mechanism of assembly and the structural changes during assembly and infection process will be described through examples of bacteriophages along with the methodology of the analyses.

(Schedule)

1. Overview of supramolecules in the cell –tight complex and association-dissociation system–
2. Hierarchical structure of proteins
3. Protein-protein interactions
4. Repeats and symmetry in protein supramolecules
5. Co-operativity in the structure formation of protein assembly
6. Structure of viruses
7. Principle of quasi-equivalence –Caspar · Klug theory–
8. Methods of analyses on assembly
1. : application of conditional lethal mutants and in vivo and in vitro complementation
9. Methods of strucutre determination
1. : electron microscopy, X-ray crystallography etc.
10. Methods of analysis in protein-protein interactions
1. : anaytical ultracentrifugation, surface plasmon resonance, isothermal titration microcalorimetry, light scattering
11. Paper review (1)
12. Paper review (2)
13. Paper review (3)
14. Summary

(How to Grade)
Attendance to the lectures and reports

82003
Advanced Course of Bioorganic Engineering
Autumn Semester (2-0-0) (Even Years)
Prof. Hisakazu MIHARA, Assoc. Prof. Tomoko MATSUDA

In the lecture 1-7, basic and advanced research status of biocatalysis is to be learned. The lecture 8-14 is regarding chemical syntheses of biomolecules, DNA & Peptide, and those applications in biotechnology.

78099
Bioscience and Biotechnology Topics 2 (2011)
Autumn Semester (1-0-0)
Prof. Minoru SAKURAI et al.

78083
Evaluation in International Perspective
Autumn Semester (2-0-0)
Assoc. Prof. Yuriko SATO

By taking this course, students can expect to deepen their understanding of major evaluation theories, their historical background and their application in the field of international development. They can also expect to acquire basic evaluation skills through the use of case studies, performing meta-evaluation and creating evaluation proposals.

81014
Advanced Course of Bioscience Communication
Autumn Semester (2-0-0)
Assoc. Prof. Naomi ARIMURA

78090
Presentation Skill for Science and Technology
Spring Semester (2-0-0)
Assoc. Prof. Martin MELDRUM

The science-Based English teacher teaches the presentation skill concerning the science and technology.
It aims to learn various techniques to explain, discuss and debate own research and development to others, and to foster ability of English presentation.

78091
IGC Bio-Internship I
Autumn Semester (0-4-0)
Assoc. Prof. Susumu KAJIWARA et al.

This class is a practical project at research institutes or corporations in Japan from three to six months.
A student must take this class or IGC Bio-Internship II.

78092
IGC Bio-Internship II
Spring Semester (0-4-0)
Assoc. Prof. Susumu KAJIWARA et al.

This class is a practical project at research institutes or corporations in Japan from three to six months.
A student must take this class or IGC Bio-Internship I.

78071
Directed Collaboration Works
Autumn Semester (2-0-0)
Assoc. Prof. Susumu KAJIWARA, Prof. Hisakazu MIHARA

To foster the creativity and planning about research and development in bioscience and biotechnology fields, and the scientific communication with other students, a student plans to develop a product with the other student(s), mainly Japanese students. A group spends two weeks to one month to finish this work. In the end of the semester, all groups have to perform oral presentations about their works.

(Given in Japanese, but international graduate course students can also attend and earn credits) Department of Life Science
Subject	Registration Number	Credit	Chair	Semester	Remarks (See footnotes)
Bio-Internship I	78030	0-0-2	Yuasa et al.	Spring	C
Bio-Internship II	78029	0-0-2	Ohta et al.	Autumn	C
Bio-Internship III	78082	0-0-2	Sato	Autumn	C
Bioinformatics (bio)	78032	2-0-0	Nakai et al.	Spring	C
Industrial Sociology	78033	2-0-0		Spring	C
Brain Science	78034	2-0-0	Matsui et al.	Spring	C
Biotechnical Reading	78035	2-0-0	Shibata	Spring	C
Biotechnical Writing	78051	2-0-0	James Watt	Spring	C
Biological Chemistry	78088	2-0-0	Kajiwara et al.	Spring
Organic Chemistry	82026	2-0-0	Mihara et al.	Spring
Physical Chemistry	79012	2-0-0	Sakurai et al.	Spring
Overseas training for R & D	78089	0-2-0	Kajiwara, Hashida et al.	Autumn
Advanced Course of Molecular Structure Analysis	78003	2-0-0	Murakami et al.	Autumn	E
Advanced Course of Molecular and Biochemical Genetics	78005	2-0-0	Iwasaki	Spring	E
Organic Chemistry of Biomolecules	78007	2-0-0	Sekine	Autumn	E
Advanced Course of Biological Physics	78009	2-0-0	Hayashi et al.	Autumn	O
Advanced Course of Medical Sciences	78028	2-0-0	Ichinose, Kajiwara	Autumn	O
Advanced Molecular Life Science	78017	2-0-0		Spring	E
Science of Radiation and Beams	93018	2-0-0	Kono et al.	Spring
Instrumental Analysis	95010	2-0-0	Naruke et al.	Spring
Environmental Microbiology	87003	2-0-0	Hisabori, Sugano	Spring
Advanced Course of Bioscience Communication	81014	2-0-0	Arimura	Autumn
GCOE Earths Special Lecture 2	18126	1-0-0	Shibuya et al.	Autumn
GCOE Earths Special Lecture 3	18127	1-0-0	Maruyama	Spring
GCOE Earths Special Lecture 5	18128	1-0-0	Ohta et al.	Spring
Project Managing Skills I	25031	2-0-0	Ohtani	Spring
Project Managing Skills III	25033	2-0-0	Furuta	Autumn
Lecture on Advanced Life Science I	78501	1-0-0		Spring	O
Lecture on Advanced Life Science II	78502	1-0-0		Spring	E
Lecture on Advanced Life Science III	78503	1-0-0		Spring	O
Lecture on Advanced Life Science IV	78504	1-0-0		Spring	E
Advanced Life Science (Integrated Doctoral Education Program)	78056	2-0-0	Kajiwara et al.	Spring
Advanced Biological Sciences (Integrated Doctoral Education Program)	78057	2-0-0	Nakamura et al.	Autumn
Advanced Biological Information (Integrated Doctoral Education Program)	78058	2-0-0
Advanced Bioengineering (Integrated Doctoral Education Program)	78059	2-0-0	Mihara et al.	Spring
Advanced Biomolecular Engineering (Integrated Doctoral Education Program)	78060	2-0-0	Sakurai et al.	Spring
Training for Bio-business and Bio-industry	78084	2-0-0	Kajiwara et al.	Spring	C
1) “E” or “O” symbols in the remarks column show that those classes are opened in even or odd years, respectively. The classes without such symbols are opened every year. Department of Biological Sciences
Subject	Registration Number	Credit	Chair	Semester	Remarks (See footnotes)
Bio-Internship I	78030	0-0-2	Yuasa et al.	Spring	C
Bio-Internship II	78029	0-0-2	Ohta et al.	Autumn	C
Bio-Internship III	78082	0-0-2	Sato	Autumn	C
Bioinformatics (bio)	78032	2-0-0	Nakai et al.	Spring	C
Industrial Sociology	78033	2-0-0		Spring	C
Brain Science	78034	2-0-0	Matsui et al.	Spring	C
Biotechnical Reading	78035	2-0-0	Shibata	Spring	C
Biotechnical Writing	78051	2-0-0	James Watt	Spring	C
Advanced Cell Biology	81001	2-0-0	Kitamura	Spring	O
Advanced Course of Biological Recognition and Signalling I	81003	2-0-0	Hirose	Spring	E
Advanced Course of Biological Recognition and Signalling II	81004	2-0-0	Nakamura et al.	Autumn	O
Choromosome Architecture & Dynamics	81017	2-0-0		Spring	O
Advanced Course of Molecular Evolution	81007	2-0-0	Okada et al.	Spring	O
Advanced Course of Genome Evolution	81008	2-0-0	Kajikawa	Spring	E
Advanced Course of Morphogenesis	81010	2-0-0	Ohta	Autumn	O
Advanced Functional Morphology	81011	2-0-0	Motokawa	Spring	O
Molecular Ecology	81012	2-0-0	Hongoh	Autumn	E
Molecular Biology	81013	2-0-0	Masuda	Spring	E
Sciences of Radiation and Beams	93018	2-0-0	Kohno et al.	Spring
Advanced Course of Bioscience Communication	81014	2-0-0	Arimura	Autumn
GCOE Earths Colloquium	18122	0-1-0	Ida, Ohmori	Autumn
GCOE Earths Status Report	18123	0-1-0	Ida, Ohmori	Autumn
GCOE Earths Internship	18124	0-0-4	Ida, Ohmori	Autumn
GCOE Earths Special Lecture 1	18125	1-0-0	Ida, Nakamoto	Spring
GCOE Earths Special Lecture 2	18126	1-0-0	Shibuya et al.	Autumn
GCOE Earths Special Lecture 3	18127	1-0-0	Maruyama	Spring
GCOE Earths Special Lecture 5	18128	1-0-0	Ohta, Maruyama	Spring
GCOE Earths International Lecture 1	18129	1-0-0		Spring
GCOE Earths International Lecture 2	18130	1-0-0		Autumn
GCOE Earths International	18131	0-1-0	Nakamoto, Ohmori	Autumn
GCOE Earths Tutorial	18132	0-0-1	Ida, Ohmori	Autumn
GCOE Earths Outreach	18133	0-1-0	Ida, Ohmori	Autumn
Project Managing Skills I	25031	2-0-0	Ohtani	Spring
Project Managing Skills Ш	25033	2-0-0	Furuta	Autumn
Advanced Course in Biosystem I	81501	1-0-0		Spring	O
Advanced Course in Biosystem II	81502	1-0-0		Spring	E
Advanced Course in Biosystem III	81503	1-0-0	Minagawa, Tokutomi	Autumn	O
Advanced Course in Biosystem IV	81504	1-0-0		Spring	E
Advanced Life Science (Integrated Doctoral Education Program)	78056	2-0-0	Kajiwara et al.	Spring
Advanced Biological Sciences (Integrated Doctoral Education Program)	78057	2-0-0	Nakamura et al.	Autumn
Advanced Biological Information (Integrated Doctoral Education Program)	78058	2-0-0
Advanced Bioengineering (Integrated Doctoral Education Program)	78059	2-0-0	Mihara et al.	Spring
Advanced Biomolecular Engineering (Integrated Doctoral Education Program)	78060	2-0-0	Sakurai et al.	Spring
Training for Bio-business and Bio-industry	78084	2-0-0	Kajiwara et al.	Spring	C
1) “E” or “O” symbols in the remarks column show that those classes are opened in even or odd years, respectively. The classes without such symbols are opened every year. Department of Biological Information
Subject	Registration Number	Credit	Chair	Semester	Remarks (See footnotes)
Bio-internship I	78030	0-0-2	Yuasa et al.	Spring	C
Bio-internship II	78029	0-0-2	Ohta et al.	Autumn	C
Bio-internship III	78082	0-0-2	Sato	Autumn	C
Bioinformatics (bio)	78032	2-0-0	Nakai et al.	Spring	C
Industrial Sociology	78033	2-0-0		Spring	C
Brain Science	78034	2-0-0	Matsui et al.	Spring	C
Biotechnical Reading	78035	2-0-0	Shibata	Spring	C
Biotechnical Writing	78051	2-0-0	James Watt	Spring	C
Advanced Molecular Cell Biology I	72001	2-0-0	Kishimoto	Autumn	E
Advanced Molecular Cell Biology II	72002	2-0-0	Tachibana	Spring	O
Medical Engineering of Biorecognition	72003	2-0-0	Handa	Autumn	E
Recent Advances in Molecular Biology	72020	2-0-0	Yamaguchi	Spring	E
Molecular Immunology and Bone Biology	72005	2-0-0	Kudo	Autumn	E
Advanced Genome Informatics	72021	2-0-0	Itoh	Spring	O
Introduction to genome information science	72018	2-0-0	Kurokawa	Spring	E
Informatic Biotechnology	72010	2-0-0	Kobatake	Spring	O
Molecular Optical Imaging	72019	2-0-0	Tokunaga	Autumn	O
Single Molecule Biology	72022	2-0-0	Sogawa	Spring	E
Advanced Course of Bioscience Communication	81014	2-0-0	Arimura	Autumn
GCOE Earths Special Lecture 2	18126	1-0-0	Shibuya et al.	Autumn
GCOE Earths Special Lecture 3	18127	1-0-0	Maruyama	Spring
GCOE Earths Special Lecture 5	18128	1-0-0	Ohta et al.	Spring
Project Managing Skills I	25031	2-0-0	Otani	Spring
Project Managing Skills III	25033	2-0-0	Furuta	Autumn
Advanced Course In Biological Information I	72501	1-0-0		Spring	O
Advanced Course In Biological Information II	72502	1-0-0		Spring	E
Advanced Course In Biological Information III	72503	1-0-0		Autumn	O
Advanced Course In Biological Information IV	72504	1-0-0		Autumn	E
Advanced Life Science (Integrated Doctoral Education Program)	78056	2-0-0	Kajiwara et al.	Spring
Advanced Biological Sciences (Integrated Doctoral Education Program)	78057	2-0-0	Nakamura et al.	Autumn
Advanced Biological Information (Integrated Doctoral Education Program)	78058	2-0-0
Advanced Bioengineering (Integrated Doctoral Education Program)	78059	2-0-0	Mihara et al.	Spring
Advanced Biomolecular Engineering (Integrated Doctoral Education Program)	78060	2-0-0	Sakurai et al.	Spring
Training for Bio-business and Bio-industry	78084	2-0-0	Kajiwara et al.	Spring	C
1) “E” or “O” symbols in the remarks column show that those classes are opened in even or odd years, respectively. The classes without such symbols are opened every year. Department of Bioengineering
Subject	Registration Number	Credit	Chair	Semester	Remarks (See footnotes)
Bio-internship I	78030	0-0-2	Yuasa et al.	Spring	C
Bio-internship II	78029	0-0-2	Ohta et al.	Autumn	C
Bio-internship III	78082	0-0-2	Sato	Autumn	C
Bioinformatics (bio)	78032	2-0-0	Nakai et al.	Spring	C
Industrial Sociology	78033	2-0-0		Spring	C
Brain Science	78034	2-0-0	Matsui et al.	Spring	C
Biotechnical Reading	78035	2-0-0	Shibata	Spring	C
Biotechnical Writing	78051	2-0-0	James Watt	Spring	C
Biological Chemistry	78088	2-0-0	Kajiwara et al.	Spring
Organic Chemistry	82026	2-0-0	Mihara et al.	Spring
Physical Chemistry	79012	2-0-0	Sakurai et al.	Spring
Overseas training for R & D	78089	0-2-0	Kajiwara, Hashida et al.	Autumn
Advanced Biochemical Process	82001	2-0-0	Kitazume	Autumn	O
Advanced Course of Cell Physiology	82004	2-0-0	Hamaguchi	Spring	E
Advanced Biofunctional Engineering	82005	2-0-0	Kamachi, Asakura	Autumn	E
Advanced Biochemical Engineering	82006	2-0-0	Tanji	Spring	E
Now and Future of Environmental Biotechnology	82007	2-0-0	Inui	Spring
Molecular Bioengineering	82008	2-0-0	Nakamura, Fukui	Spring	O
Advanced Course of Cell Technology	82011	2-0-0	Wachi	Autumn	O
Sciences of Radiation and Beams	93018	2-0-0	Kohno, et al.	Spring
GCOE Earths Special Lecture 2	18126	1-0-0	Shibuya et al.	Autumn
GCOE Earths Special Lecture 3	18127	1-0-0	Maruyama	Spring
GCOE Earths Special Lecture 5	18128	1-0-0	Ohta et al.	Spring
Project Managing Skills I	25031	2-0-0	Ohtani	Spring
Project Managing Skills III	25033	2-0-0	Furuta	Autumn
Advanced Course in Bioengineering I	82501	1-0-0		Spring	O
Advanced Course in Bioengineering II	82502	1-0-0		Spring	E
Advanced Course in Bioengineering III	82503	1-0-0		Autumn	O
Advanced Course in Bioengineering IV	82504	1-0-0		Autumn	E
Advanced Life Science (Integrated Doctoral Education Program)	78056	2-0-0	Kajiwara et al.	Spring
Advanced Biological Sciences (Integrated Doctoral Education Program)	78057	2-0-0	Nakamura et al.	Autumn
Advanced Biological Information (Integrated Doctoral Education Program)	78058	2-0-0
Advanced Bioengineering (Integrated Doctoral Education Program)	78059	2-0-0	Mihara et al.	Spring
Advanced Biomolecular Engineering (Integrated Doctoral Education Program)	78060	2-0-0	Sakurai et al.	Spring
Training for Bio-business and Bio-industry	78084	2-0-0	Kajiwara et al.	Spring	C
1) “E” or “O” symbols in the remarks column show that those classes are opened in even or odd years, respectively. The classes without such symbols are opened every year. Department of Biomolecular Engineering
Subject	Registration Number	Credit	Chair	Semester	Remarks (See footnotes)
Bio-internship I	78030	0-0-2	Yuasa et al.	Spring	C
Bio-internship II	78029	0-0-2	Ohta et al.	Autumn	C
Bio-internship III	78082	0-0-2	Sato	Autumn	C
Bioinformatics (bio)	78032	2-0-0	Nakai et al.	Spring	C
Industrial Sociology	78033	2-0-0		Spring	C
Brain Science	78034	2-0-0	Matsui et al.	Spring	C
Biotechnical Reading	78035	2-0-0	Shibata	Spring	C
Biotechnical Writing	78051	2-0-0	James Watt	Spring	C
Training for Bio-business and Bio-industry	78084	2-0-0	Kajiwara et al.	Spring	C
Biological Chemistry	78088	2-0-0	Kajiwara et al.	Spring
Organic Chemistry	82026	2-0-0	Mihara et al.	Spring
Physical Chemistry	79012	2-0-0	Sakurai et al.	Spring
Overseas training for R&D	78089	0-2-0	Kajiwara, Hashida et al.	Autumn
Measurement of Biomolecules	79001	2-0-0	Taguchi	Spring	E
Advanced Physical Chemistry of Biomolecules	79002	2-0-0		Autumn	E
Biological Computational Chemistry	79003	2-0-0	Sakurai, Nakamura	Spring	O
Biophysical Chemistry	79004	2-0-0	Ohtani	Spring	O
Biomimetic Chemistry	79005	2-0-0	Okahata, Mori	Spring	O
Artificial Bioorganic Chemistry	79006	2-0-0	Mori, Okahata	Spring	E
Advanced Biofunctional Materials	79007	2-0-0	Akaike	Autumn	E
Biofunctional Molecule Design	79008	2-0-0	Tagawa	Spring	O
Molecular Design of Biological Importance	79010	2-0-0	Urabe	Spring	E
GCOE Earths Special Lecture 2	18126	1-0-0	Shibuya et al.	Autumn
GCOE Earths Special Lecture 3	18127	1-0-0	Maruyama	Spring
GCOE Earths Special Lecture 5	18128	1-0-0	Ohta, Maruyama	Spring
Project Managing Skills I	25031	2-0-0	Ohtani	Spring
Project Managing Skills III	25033	2-0-0	Furuta	Autumn
Advanced Course in Biomolecular Engineering I	79501	1-0-0		Spring	O
Advanced Course in Biomolecular Engineering II	79502	1-0-0		Spring	E
Advanced Course in Biomolecular Engineering III	79503	1-0-0		Autumn	O
Advanced Course in Biomolecular Engineering IV	79504	1-0-0		Autumn	E
Advanced Life Science (Integrated Doctoral Education Program)	78056	2-0-0	Kajiwara et al.	Spring
Advanced Biological Sciences (Integrated Doctoral Education Program)	78057	2-0-0	Nakamura et al.	Autumn
Advanced Biological Information (Integrated Doctoral Education Program)	78058	2-0-0
Advanced Bioengineering (Integrated Doctoral Education Program)	78059	2-0-0	Mihara et al.	Spring
Advanced Biomolecular Engineering (Integrated Doctoral Education Program)	78060	2-0-0	Sakurai et al.	Spring
1) “E” or “O” symbols in the remarks column show that those classes are opened in even or odd years, respectively. The classes without such symbols are opened every year.