Ÿ Biomolecular Science Course

 

Biomolecular Science Course, International Graduate Course, is based on the Graduate School of Bioscience and Biotechnology, which consists of five departments, i.e., Department of Life Science, Department of Biological Science, Department of Biological Information, Department of Bioengineering, and Department of Biomolecular Engineering. Each student of the Biomolecular Science Course belongs to one of these departments and studies according to the curriculum of corresponding department.  As listed below, many classes are given in English, and 10 of these indicated as gCh in the remarks column of the list are common to all Departments.

 

Classes in this list are given in English.

Class Name

Credit

Lecturer(s)

Semester

Remarks

Advanced Bioorganic Chemistry

2-0-0

Kitazume, et al.

Autumn

E, C

Advanced Molecular Biology

2-0-0

Kudou, et al.

Autumn

E, C

Advanced Bioengineering

2-0-0

Tanji, et al.

Autumn

E, C

Advanced Life Science Frontiers

2-0-0

 

Spring

E, C

Bioscience and Biotechnology Topics 2005A

1-0-0

Ohta et al.

Spring

C

Bioscience and Biotechnology Topics 2005

1-0-0

Nureki et al.

Autumn

C

Synthesis of Bioactive Substances

2-0-0

Yuasa

Autumn

E

Genome-based Drug Discovery

2-0-0

Ishikawa

Spring

E

Bio-Nanomechanics

2-0-0

Ikai

Spring

E

Advanced Cell Biochemistry

2-0-0

Komada

Spring

E

Bioscience and Biotechnology International Communication I

2-0-0

Roger Prior

Spring

O, C

Bioscience and Biotechnology International Communication II

2-0-0

 

Spring

E, C

Advanced Course of Bioscience Communication

2-0-0

Arimura

Autumn

 

Advanced Biophysical Chemistry

2-0-0

Ikai, et al,

Autumn

O, C

Advanced Biochemistry

2-0-0

Akaike, et al.

Autumn

O, C

Advanced Biology

2-0-0

Tanaka, et al.

Autumn

O, C

Advanced Biotechnology Frontiers

2-0-0

Tamanoi

Spring

O, C

Advanced Course of Biological Recognition and Signaling II

2-0-0

Saito

Autumn

O

Asymmetric Synthesis

2-0-0

Kobayashi

Autumn

O

Structure and Function of Biological Supramolecules

2-0-0

Arisaka

Spring

O

 

gEh or gOh in the remarks column shows that those classes are open in even or odd year, respectively, The classes without such symbols are open every year. gCh in the remarks column indicate the class common to all department.

 

 

Ÿ Biomolecular Science Course

 

 

<2005 Autumn Semester>

 

Advanced Bioorganic Chemistry (2-0-0)

2nd period of odd year     

Prof. Tomoya Kitazume, Prof. Hirokazu Urabe, Associate Prof. Yuichi Kobayashi, and

Associate Prof. Tomoko Matsuda

 

(Aim)

In addition to analyze bioorganic molecules and/or organic molecules, their synthesis is a next critical step to take advantage of these molecules in a more positive way.  Actually, derivatives of these molecules, which are solely obtained by the artificial synthesis, often prove much more useful than the original biomolecules.  In this lecture, such an essential field of organic chemistry, i.e., how to construct and design our own biomolecules, will be discussed.

 

(Schedule)

1. Introduction, what are molecular recognitions?

2. Molecular recognition of enzymes (1)

3. Molecular recognition of enzymes (2)

4. Molecular recognition of enzymes (3)

5. Synthesis and design of small biomolecules (1)

6. Synthesis and design of small biomolecules (2)

7. New trends in organic synthesis (1)

8. New trends in organic synthesis (2)

9. New trends in organic synthesis (3)

10. New trends in organic synthesis (4)

11. Synthesis of classical prostaglandins

12. Synthesis of new prostaglandins and other cyclopentanoids

 

(How to Grade)

Attendance and reports (and possibly examination?)

(Text, etc.)

Necessary stuff for this class will be provided by the lecturers.

 

Advanced Molecular Biology (2-0-0)

Even Years  2nd Semester

 

Prof. Kazuo SHISHIDO (Bldg B1 Flr 7th Rm701, ext.5714) , Prof. Akira KUDO (Bldg B1 Flr 6th Rm601, ext.5718),  and Associate Prof. Yasunori AIZAWA (Bldg B1 Flr 7th Rm712, ext5787)

 

(Aim)

  The course will be given in English and open to the students belonging to not only the International Graduate Course but also to the regular course. The course consists of the three academic/research fields which will be presented by the three professors of the Graduate Course of Bioscience. Each of the fields contains several topics.

 

(Schedule)

I. Molecular Biology and Biotechnology of Basidiomycete Fungi (Prof. K. Shishido)

1. Introduction to basidiomycete fungi

2. Molecular mechanism of morphological differentiation (fruiting body formation)

3. Regulation of gene expression

4. Molecular breeding of the fungal strains useful for reuse of waste plant biomass and degradation of chlorinated        aromatic compounds

II. Molecular Aspects of Immunology and Bone Biology (Prof. A. Kudo)

1. Introduction of Immunology

2. B cell and T cell differentiation

3. Introduction of Bone Biology

4. Osteoblast and Osteoclast differentiation

III. Modern Molecular Genomics (Associate Prof. Y. Aizawa)

1. Mammalian Genome Architecture

2. Shaping Mammalian Genome by Mobile Genetic Elements

3. Introduction of Non-coding RNA

4. MicroRNA World

 

(How to Grade)

  Attendance and reports

 

 Advanced Bioengineering (2-0-0)

2nd period of even year

Assoc. Prof. Yasunori TANJI, Assoc. Prof. Toshiaki FUKUI, and Assoc. Prof. Toshiaki KAMACHI

 

(Aim)

 Most advanced research status of bioengineering is to be learned, where bio-functions derived from biological elements such as viruses/phages, enzymes, microbes, plant/animal cells are applied to the construciton of innovative systems for producing materials and/or energy, and contributing environmental technology.

 

(Schedule)

 1. Mechanism and application of biocatalysis

   1-1  Kinetics of biocatalytic reactions

   1-2  Mechanism of biocatalytic reactions

   1-3  Production of useful materials with biocatalysts

   1-4  Pront of industrial production with biocatalysts

 2. Molecular bioengineering of extremozymes and related proteins

   2-1  Methodology for effcient foreign gene expression

   2-2  Extremophiles and extremozymes

   2-3  Protein engineering of extremozymes and related proteins

   2-4  Directed evolution of extremozymes and related proteins

3. Environmental bioengineering

   3-1  Biogeochemical cycles in the earth surface

   3-2  Biological conversion of the waste by microbiota (I)

   3-3  Biological conversion of the waste by microbiota (II)

   3-4  Roles of bacterophage in the bacterial ecosystem and its engineering application

 

Synthesis of Bioactive Substances (2-0-0) Even year

Associate Prof. Hideya YUASA

(Aim)

Organic synthesis is one of the most powerful tools to create drugs for diseases, such as cancer, diabetes, flu, and etc. Thus the knowledge and skills of organic synthesis are prerequisite for the research in pharmaceutical industry. The aim of this class is to have you understand the logics and mechanisms underlying the design and synthesis of bioactive molecules. To make the class less bored, each lecture will deal with the synthesis of a few compounds, with which the basic principles behind the constituent reactions will be uncovered. Therefore, you do not have to attend all of the classes. The first half of this class will be based on the text book, gTop Drugs: Top Synthetic Routesh (John Saunders, Oxford University Press: Oxford, 2000). Our own research results are discussed in the latter half.

(Schedule)

1. Inhibitors of angiotensin converting enzyme

2. Blockade of angiotensin-II receptors

3. Calcium channel blockers

4. Antagonists of histamine receptors

5. Proton pump inhibitors

6. Modulation of central serotonin

7. Ligands for benzodiazepine receptor

8. Blockers of the H1 recptor

9. Inhibitors of HIV reverse transcriptase

10. Anti-bacterial DNA gyrase inhibitors

11. Glycosidase inhibitors against diabetes

12. Carbohydrate-based future drugs

13. Principles of mimics and mimetics

14. Dynamic molecules for future drugs

15. Peptide synthesis (optional)

 

(How to grade)

Attendance and report

 

Genome-based Drug Discovery (Even year)

Prof. Toshihisa Ishikawa

 

 (Aim)

In the 21st century, emerging genomic science and technologies are shifting the paradigm of drug discovery research and improving the strategy of medical care for patients.  In order to realize the personalized medicine, it is critically important to understand molecular mechanisms underlying inter-individual differences in the drug response, namely, pharmacological effect vs. side effect.  Pharmacogenomics, the study of influence of genetic factors on drug action, is increasingly important for predicting pharmacokinetics profiles and/or adverse reactions of drugs.

In this lecture series, basic science underlying the genome-based drug discovery and current critical issues will be presented and mutually discussed.

 

 (Schedule)

1. Introduction: History of drug discovery research (lecture)

2. Genome-based drug discovery (lecture)

3. Target validation and high throughput screening (lecture)

4. Presentation and free discussion

4. Medicinal chemistry (lecture)

5. Presentation and free discussion

6. Pharmacology and toxicology (lecture)

7. Presentation and free discussion

8. Pharmacogenomics (lecture)

9. Presentation and free discussion

10. Recent topics (lecture)

11. Business strategies of pharmaceutical companies (lecture)

12. Presentation and free discussion

 

 (How to grade)

Graduate students are expected to attend lectures and to actively participate in discussion.  Following lectures, graduate students will be requested to present their own reports on particular subjects, such as target validation and high throughput screening, medicinal chemistry, pharmacology and toxicology, pharmacogenomics, and business strategies of pharmaceutical companies.  Lecture, presentation, and discussion will be provided in English only (no Japanese!).

 

(Text)

gPharmacogenomicsh (Eds.: W. Kalow, U.A. Meyer, R.F. Tyndale) Marcel Dekker, Inc. New York/Basel.

 

Bio-Nanomechanics (Even year)

Professor Atushi IKAI

 

This course is given by Ikai and introduces a mechanical view on biostructures made of proteins, nucleic acids, polysaccharides and lipids.Knowledge in mechanics is helpful but the basis will be given whenever necessary.

 

(Schedule)

1. Introduction to Basic Biomechanics

2. Mechanics of the Cell

3. Mechanics of the Cell and Cell Models

4. Red Blood Cell

5. Movements of the Cell

6. Cell Membranes

7. Membrane Proteins

8. Single Molecule Mechanics (1) Proteins

9. Single Molecule Mechanics (2) Proteins

10. Single Molecule Mechanics (3) DNA

11. Self-assembly of Biomolecules

12. Other Topics in Biomechanics

 

Advanced Cell Biochemistry (2-0-0) Even year

Assoc. Prof. Masayuki KOMADA

(Aim)

Membrane traffic is a cellular process by which proteins are transported from an organelle to another in a constitutive or regulated manner.  Precise transport of proteins to their destinations is essential for cellular function.  This course focuses on the molecular mechanisms of various membrane traffic processes in eukaryotic cells.  The mechanisms of localizing specific proteins at specific cellular membranes will also be addressed.  Equal efforts will be made to address the fundamentals and recent findings on each subject.

 

(Schedule)

2. Endocytosis

3. Traffic of newly-synthesized lysosomal enzymes from the Golgi

4. Sorting of lysosome-targeted proteins at the endosome and downregulation of signaling receptors

5. Rab family of small GTP-binding proteins

6. Regulation of protein localization by phosphatidylinositol phosphates

7. Autophagy

7. Kinesin-mediated axonal transport

8. Regulation of membrane protein localization by PDZ domain proteins

9. Regulation of membrane protein localization by spectrin membrane skeleton

 

(How to Grade)

attendance, tests

 

(Text, etc.)

 

(Message from a Lecturer)

 

 

<2005 Autumn Semester>

 

Advanced Biophysical Chemistry (2-0-0)

2nd period of odd year

This course is given by Profs. Atsushi IKAI, Kohsaku SUGA, and Akio TAKENAKA and deals with recent advancement and related topics from the field of biophysical chemistry.

 

(Schedule)

I Microscopes used in Bioscience and Biotechnology (Atsushi Ikai)

 1. Basics of Microscopy: Physical and Geometrical Optics

 2. Light Microscopes:

Phase constrast M., Confocal M., Fluorescnece M.

 3. Electron Microscopes:

Transmission EM., Scanning EM.

 4. Probe Microscopes:

Scannning Tunneling M., Atomic Force M.,Force Spectroscopy.

II Energetics in Bioscience and Biotechnology (Kosaku Suga)

 5. Thermodynamic basis of bioenergetics

1.Redox potentials and free energy changes

 6. Thermodynamic basis of bioenergetics

2.Membrane potential and storage of energy

 7. Energy conversion in biosystem

1.Coupled electron transfer and proton transfer in electron

        transport system

 8. Energy conversion in biosystem

2.Fundamental aspect of electron transfer reactions in photosynthesis

III Structural Biology (Akio Takenaka)

9. Structure biology of the RNA world

10. Structure biology of the protein world

11. X-Ray crystallography for structure biology Part 1.

12. X-Ray crystallography for Structure biology Part 2.

 

Advanced Biochemistry (2-0-0)

2nd period of odd year

Prof. Toshihiro AKAIKE, Assoc. Prof. Masayuki KOMADA, and Prof. Hiroshi ICHINOSE

This course will be given in English. Major areas of contemporary biochemistry will be covered to help understand the chemical basis of life. The themes include (1) Biochemistry of Cell Community, (2) Biochemistry of growth factor signaling, and (3)Metabolism of amino acids and monoamines

 

(Schedule)

Prof. AKAIKE: Biochemistry of Cell Community

1. Cell Surface Chemistry

2. Cell-matrix interactions

3. Cell-Cell Interactions

4. Cellular Engineering and Tissue Engineering

 

Prof. KOMADA: Biochemistry of growth factor signaling

1. peptide growth factors and their receptors

2. signaling from tyrosine kinase-type receptors

3. signaling from other types of receptors

4. receptor downregulation

 

Prof. ICHINOSE: Metabolism of amino acids and monoamines

1. amino acid metabolism

2. vitamines involved in amino acid metabolism

3. monoamine neurotransmitters

4. monoamines and neurological disorders

 

(How to Grade)

attendance, class participation, reports, and tests

 

Advanced Biology (2-0-0) Odd year

2nd period of odd year

This course will be given in English. Major areas of contemporary biology will cover to help understand the modern biology. The themes include (1) Developmental Biology, (2) Cell and Population Biology, and (3) Evolutionary Biology and Plant Sciences.

 

Associate Prof. Mikiko TANAKA,  Prof. Yukihisa HAMAGUCHI, and Associate

Prof. Hiroyuki OHTA

 

(Aim)

Cellular and molecular mechanisms that regulate animal development will be

studied. Main focus will be on principles for establishment of the body

plan and formation of selected organs (M. Tanaka).

 

The structure and fuction of a cell will be studied using a example of cell

division (Y. Hamaguchi).

 

(Schedule)

1. Developmental anatomy of early embryos

2. Organogeneis I

3. Organogeneis II

4. Organogenesis III

5. Cell, its structure and function

6. How to observe a cell: Optical microscopy

7. How to examine a cell: Micromanipulation

8. Process and mechanism of cell division

9. Evolution of photosynthetic organisms

10. Plant chloroplasts: their function and biogenesis (1)

11. Plant chloroplasts: their function and biogenesis (2)

12. Methods for transformation of plant cells

 

(How to Grade)

 Attendance and reports

 

 (Text, etc.)

 Lecturers will prepare prints, if necessary.

 

 

<2005 Autumn Semester>

 

Advanced Course of Biological Recognition and Signaling II (2-0-0) Odd year

Assoc. Prof. Yuji SAITO

(Aim)

Students will learn the up-to-date knowledge and the ways to carry out research about biological signal transduction. This object could be attained not only from the lectures given by the instructor but also by actively participating in a series of presentations given by fellow students.

(Schedule)

1. Give basic and general understanding about Biological Signal Transduction. (2 weeks)

Explain various receptors and molecules involved in different biological signal transduction pathways, and cross-talks among them.

2. Discuss about various oncogenes and tumor suppressors with regard to apoptosis, differentiation and cancer, based on topics published in recent literatures. (2 weeks)

3. Students are expected to make a bit formal presentations about a series of subjects chosen from current literature. Students will learn from this experience how to write and read papers as well as how to give a talk in conferences. (8 weeks)

 

(How to grade)

Students are expected to attend lectures as often as possible, and actively participate in the discussion about the topics presented by fellow students.

 

Asymmetric Synthesis (2-0-0) Odd year

Associate Prof. Yuichi KOBAYASHI

(Aim)

Asymmetric reaction is one of the most powerful methods to prepare chiral compounds.   Presented herein is some of the efficient asymmetric reactions by which high enantiomeric excess of the products is attained.   The principle and the mechanism for the creation of chiral centers in the molecules are also discussed. 

(Schedule)

1. Fundamental Aspects of Asymmetric Synthesis

2. Preparation of Chiral Compounds by means of Optical Resolution, Asymmetric Synthesis, Chiral

Pool Method, Reactions using Enzymes

3. Diastereoselection and Enantioselection

4. Selectivity in the Enolate Formation and the Asymmetric Alkylation

5. Asymmetric Aldol Condensations: Part 1

6. Asymmetric Aldol Condensations: Part 2

7. Catalytic Asymmetric Reactions: Part 1:

Hydrogenation, Isomerization, Allylic Substitution

8. Catalytic Asymmetric Reactions: Part 2:

Cyclopropanation, Diels-Alder Reaction

9. Asymmetric Epoxidation

10. Transformations of Epoxides

11. Asymmetric Dihydroxylation

12. Asymmetric Reactions of Compounds with Symmetry Elements

13. Chiral Pool Method

14. Asymmetric Synthesis of Biologically Active Compounds

15. Summary

 

(How to grade)

Attendance and report

 

Structure and Function of Biological Supramolecules (2-0-0)

1st period of odd year

Associate Professor Fumio ARISAKA

(Aim)

Among biological supramolecules, focus will be made on the protein supramolecules and the mechanisms and principles that control the molecular assembly and the methods of analyses will be taught. First, hierarchical structure of proteins will be introduced and varieties of interactions involved in the formation of protein supramolecules will be explained. After describing the various structures in the cell, structure of viruses will be introduced and the mechanism of assembly and the structural changes during assembly and infection process will be described through examples of bacteriophages along with the methodology of the analyses.

(Schedule)

1. Overview of supramolecules in the cell

    |tight complex and association-dissociation system|

2. Hierarchical structure of proteins

3. Protein-protein interactions

4. Repeats and symmetry in protein supramolecules

5. Co-operativity in the structure formation of protein assembly

6. Structure of viruses

7. Principle of quasi-equivalence

    |CasparEKlug theory|

8. Methods of analyses on assemblyFapplication of conditional lethal mutants and in vivo and in vitro complementation

9. Methods of strucutre determinationFelectron microscopy, X-ray crystallography etc.

10. Mehtods of analysis in protein-protein interactionsFanaytical ultracentrifugation, surface plasmon resonance, isothermal titration microcalorimetry, light scattering

11. paper review (1)

12. paper review (2)

13. paper review (3)

14. Summary

(How to Grade)

Attendance to the lectures and reports

 

 

List of Normal-course Lectures (Given in Japanese, but international graduate course students can also attend

and ean credits)

 

Department of Life Science

 

Class

Credit

Lecturer

Semester

Note

Bio-intern Ship I

0-0-2

Ohta et al.

 

Spring

C

Bio-intern Ship II

0-0-2

Ohta et al.

Spring

C

Bioinformatics

2-0-0

Tabata et al.

Spring

C

Industrial Sociology

2-0-0

Nureki et al.

Spring

C

Brain Science

2-0-0

Matsui et al.

Spring

C

Biotechnical Reading

2-0-0

Shibata

Spring

C

Synthesis of Bioactive Substances

2-0-0

Yuasa

Autumn

E

Advanced Course of Molecular Structure Analysis

2-0-0

Kumasaka

Spring

E

Advanced Structural Biology

2-0-0

Takenaka

Autumn

O

Advanced Course of Biochemical Genetics

2-0-0

Shishido

Spring

E

Advanced Course of Molecular Regulation

2-0-0

Kajiwara

Spring

O

Organic Chemistry of Biomolecules

2-0-0

Sekine

Autumn

E

Molecular Recognition of Biomolecules

2-0-0

Seio

Spring

O

Advanced Course of Biological Physics

2-0-0

Osada

Spring

E

Bio-Nanomechanics

2-0-0

Ikai

Spring

E

Advanced Course of Medical Chemistry

2-0-0

Ichinose

Autumn

O

Advanced Molecular Life Science

2-0-0

Yamashita

Spring

E

Science of Radiation and Beams

2-0-0

Ogawa

Spring

 

Instrumental Analysis

2-0-0

Mori

Spring

 

Biochemistry

2-0-0

Yoshida

Autumn

 

Advanced Course of Bioscience Communication

2-0-0

Arimura

Autumn

 

Chemistry of the oxygen atmosphere

1-0-0

Maruyama, et al.

Autumn

 

Science of Photosynthetic Organisms

1-0-0

Maruyama, Ohta

Spring

 

History of life and modern life under extreme environments

1-0-0

Maruyama, Kohshima

Spring

 

Project Managing Skills I

2-0-0

Kadota

Spring

 

Project Managing Skills IV

2-0-0

Furuta

Autumn

 

Lecture on Advanced Life Science 1

1-0-0

 

Spring

O

Lecture on Advanced Life Science 2

1-0-0

 

Spring

E

Lecture on Advanced Life Science 3

1-0-0

 

Spring

O

Lecture on Advanced Life Science 4

1-0-0

 

Spring

E

Directed Laboratory Works in Life Science 1

0-0-2

 

Spring

Master's Course ‡@

Directed Laboratory Works in Life Science 2

0-0-2

 

Autumn

Master's Course ‡@

Seminar in Life Science 1

1

 

Spring

Master's Course ‡@

Seminar in Life Science 2

1

 

Autumn

Master's Course ‡@

Seminar in Life Science 3

1

 

Spring

Master's Course ‡A

Seminar in Life Science 4

1

 

Autumn

Master's Course ‡A

Seminar in Life Science 5

1

 

Spring

Doctoral Course ‡@

Seminar in Life Science 6

1

 

Autumn

Doctoral Course ‡@

Seminar in Life Science 7

1

 

Spring

Doctoral Course ‡A

Seminar in Life Science 8

1

 

Autumn

Doctoral Course ‡A

Seminar in Life Science 9

1

 

Spring

Doctoral Course ‡B

Seminar in Life Science 10

1

 

Autumn

Doctoral Course ‡B

Advanced Biology

2-0-0

Chujyo

Spring

Tsinghua University

Advanced Biochemistry

2-0-0

Wang

Spring

Tsinghua University

Advanced Structural Biology

2-0-0

Takenaka

Spring

Tsinghua University

Molecular Recognition on Biomolecules

2-0-0

Kudo

Spring

Tsinghua University

Advanced Bioorganic Chemistry

2-0-0

Chujyo

Spring

Tsinghua University

Advanced Molecular Biology

2-0-0

Wang

Spring

Tsinghua University

Advanced Biofunctional Materials

2-0-0

Akaike

Spring

Tsinghua University

Bioengineering Now

2-0-0

 

Spring

Tsinghua University

 

 

Department of Biological Sciences

 

Class

Credit

Lecturer

Semester

Note

Bio-intern Ship I

0-0-2

Ohta et al.

 

Spring

C

Bio-intern Ship II

0-0-2

Ohta et al.

Spring

C

Bioinformatics

2-0-0

Tabata et al.

Spring

C

Industrial Sociology

2-0-0

Nureki et al.

Spring

C

Brain Science

2-0-0

Matsui et al.

Spring

C

Biotechnical Reading

2-0-0

Shibata

Spring

C

Advanced Course of Biological Substances

2-0-0

 

Spring

O

Advanced Cell Biochemistry

2-0-0

Komada

Spring

E

Advanced Course of Biological Recognition and Signalling I

2-0-0

Hirose

Spring

E

Advanced Course of Biological Recognition and Signalling II

2-0-0

Saito

Autumn

O

Choromosome Architecture & Dynamics

2-0-0

Shirahige

Spring

O

Advanced Course of Molecular Developmental Biology

2-0-0

Tanaka

Autumn

E

Advanced Course of Molecular Evolution

2-0-0

Okada

Spring

O

Genetic Informatics

2-0-0

Okada

Spring

E

Photobioenergetics

 

2-0-0

Takamiya

Spring

E

Advanced Course of Morphogenesis

2-0-0

Ohta

Autumn

O

Advanced Functional Morphology

2-0-0

Motokawa

Spring

O

Advanced Course of Ecology

2-0-0

Kohshima

Autumn

E

Molecular Biology

2-0-0

Sakaki, et al.

 

Spring

O

Sciences of Radiation and Beams

2-0-0

Ogawa, et al.

Spring

 

Advanced Course of Bioscience Communication

2-0-0

Arimura

Autumn

 

Advanced Course in Biosystem I

1-0-0

 

Spring

O

Advanced Course in Biosystem II

1-0-0

 

Spring

E

Advanced Course in Biosystem III

1-0-0

 

Autumn

O

Advanced Course in Biosystem IV

1-0-0

 

Spring

E

Advanced Experiments of Biosystem I

0-0-2

Mentor

Spring

Master's Course ‡@

Advanced Experiments of Biosystem II

0-0-2

Mentor

Autumn

Master's Course ‡@

Seminar in Biosystem I

1

Mentor

Spring

Master's Course ‡@

Seminar in Biosystem II

1

Mentor

Autumn

Master's Course ‡@

Seminar in Biosystem III

1

Mentor

Spring

Master's Course ‡A

Seminar in Biosystem IV

1

Mentor

Autumn

Master's Course ‡A

Seminar in Biosystem V

1

Mentor

Spring

Doctoral Course ‡@

Seminar in Biosystem VI

1

Mentor

Autumn

Doctoral Course ‡@

Seminar in Biosystem VII

1

Mentor

Spring

Doctoral Course ‡A

Seminar in Biosystem VIII

1

Mentor

Autumn

Doctoral Course ‡A

Seminar in Biosystem IX

1

Mentor

Spring

Doctoral Course ‡B

Seminar in Biosystem X

1

Mentor

Autumn

Doctoral Course ‡B

Seminar in Biosystem X

1

Mentor

Autumn

Doctoral Course ‡B

Advanced Biology

2-0-0

Chujyo

Spring

Tsinghua University

Advanced Biochemistry

2-0-0

Wang

Spring

Tsinghua University

Advanced Structural Biology

2-0-0

Takenaka

Spring

Tsinghua University

Molecular Recognition on Biomolecules

2-0-0

Kudo

Spring

Tsinghua University

Advanced Bioorganic Chemistry

2-0-0

Chujyo

Spring

Tsinghua University

Advanced Molecular Biology

2-0-0

Wang

Spring

Tsinghua University

Advanced Biofunctional Materials

2-0-0

Akaike

Spring

Tsinghua University

Bioengineering Now

2-0-0

 

Spring

Tsinghua University

 

 

1)  The classes with symbols should be passed in the indicated academic years. ‡@, ‡A, ‡B in

the remarks column indicate academic years.

2)  gEh or gOh symbols in the remarks column show that those classes are opened in even or odd

years, respectively. The classes without such symbols are opened every year.

 

 

Department of Biological Information

 

 

Class

Credit

Lecturer

Semester

Note

Bio-intern Ship I

0-0-2

Ohta et al.

 

Spring

C

Bio-intern Ship II

0-0-2

Ohta et al.

Spring

C

Bioinformatics

2-0-0

Tabata et al.

Spring

C

Industrial Sociology

2-0-0

Nureki et al.

Spring

C

Brain Science

2-0-0

Matsui et al.

Spring

C

Biotechnical Reading

2-0-0

Shibata

Spring

C

Advanced Molecular Cell Biology I

2-0-0

Kishimoto

Autumn

E

Advanced Molecular Cell Biology II

2-0-0

Ohsumi

Autumn

O

Medical Engineering of Biorecognition

 

2-0-0

Handa

Spring

E

Genetic Information Engineering

2-0-0

Wada

Spring

O

Molecular Immunology and Bone Biology

2-0-0

Kudo

Spring

E

Advanced Developmental Genetics

2-0-0

Imai

Spring

O

Structual Biology

2-0-0

Nureki

Autumn

O

Fundamental Bioinformatics

2-0-0

Tateno

Autumn

E

Informatic Biotechnology

2-0-0

Kobatake

Spring

O

Ecological Information Processing I

2-0-0

 

Spring

O

Ecological Information Processing II

2-0-0

 

Spring

E

Advanced Cell and Molecular Biology I

2-0-0

Setou

Autumn

E

Advanced Cell and Molecular Biology II

2-0-0

Kanie

Spring

O

Advanced Course of Bioscience Communication

2-0-0

Arimura

Autumn

 

Chemistry of the oxygen atmosphere

1-0-0

Maruyama, et al.

Autumn

 

Science of Photosynthetic Organisms

1-0-0

Maruyama, Ohta

Spring

 

History of life and modern life under extreme environments

1-0-0

Maruyama, Kohshima

Spring

 

Project Managing Skills I

2-0-0

Kadota

Spring

 

Project Managing Skills IV

2-0-0

Furuta

Autumn

 

Advanced Course In Biological Information I

1-0-0

Nagata

Spring

O

Advanced Course In Biological Information II

1-0-0

 

Spring

E

Advanced Course In Biological Information III

1-0-0

Kageyama, Yasuda

Autumn

O

Advanced Course In Biological Information IV

1-0-0

 

Autumn

E

Advanced Experiments of Biological Information I

0-0-2

 

Spring

Master's Course ‡@

Advanced Experiments of Biological Information II

0-0-2

 

Autumn

Master's Course ‡@

Seminars in Biological Information I

1

 

Spring

Master's Course ‡@

Seminars in Biological Information II

1

 

Autumn

Master's Course ‡@

Seminars in Biological Information III

1

 

Spring

Master's Course ‡A

Seminars in Biological Information IV

1

 

Autumn

Master's Course ‡A

Seminars in Biological Information V

1

 

Spring

Doctoral Course ‡@

Seminars in Biological Information VI

1

 

Autumn

Doctoral Course ‡@

Seminars in Biological Information VII

1

 

Spring

Doctoral Course ‡A

Seminars in Biological Information VIII

1

 

Autumn

Doctoral Course ‡A

Seminars in Biological Information VIIII

1

 

Spring

Doctoral Course ‡B

Seminars in Biological Information X

1

 

Autumn

Doctoral Course ‡B

Advanced Biology

2-0-0

Chujyo

Spring

Tsinghua University

Advanced Biochemistry

2-0-0

Wang

Spring

Tsinghua University

Advanced Structural Biology

2-0-0

Takenaka

Spring

Tsinghua University

Molecular Recognition on Biomolecules

2-0-0

Kudo

Spring

Tsinghua University

Advanced Bioorganic Chemistry

2-0-0

Chujyo

Spring

Tsinghua University

Advanced Molecular Biology

2-0-0

Wang

Spring

Tsinghua University

Advanced Biofunctional Materials

2-0-0

Akaike

Spring

Tsinghua University

Bioengineering Now

2-0-0

 

Spring

Tsinghua University

 

Department of Bioengineering

 

Class

Credit

Lecturer

Semester

Note

Bio-intern Ship I

0-0-2

Ohta et al.

 

Spring

C

Bio-intern Ship II

0-0-2

Ohta et al.

Spring

C

Bioinformatics

2-0-0

Tabata et al.

Spring

C

Industrial Sociology

2-0-0

Nureki et al.

Spring

C

Brain Science

2-0-0

Matsui et al.

Spring

C

Biotechnical Reading

2-0-0

Shibata

Spring

C

Advanced Biochemical Process

2-0-0

Kitazume and Matsuda

Autumn

O

Structure and Function of Supramolecules

2-0-0

Arisaka

Spring

O

 

Advanced Course of Biopolymers

2-0-0

Mihara

Autumn

E

Advanced Course of Cell Physiology

2-0-0

Hamaguchi

Spring

E

Advanced Biofunctional Engineering

2-0-0

Okura and Kamachi

 

Autumn

E

Advanced Biochemical Engineering

2-0-0

Tanji

Spring

E

Now and Future of Environmental Biotechnology

2-0-0

Miya

Spring

 

Molecular Bioengineering

2-0-0

Fukui

Spring

O

Advanced Protein Engineering

2-0-0

Nakamura

Autumn

E

Advanced Course of Cell Technology

2-0-0

Wachi

Autumn

O

Neuronal Bioengineering

1-0-0

Hisatsune

Spring

 

Science of Radiation and Beams

2-0-0

Ogawa, et al.

Spring

 

COE Earth Program :Special Colloquium 1

 

1-1-0

 

Spring

 

COE Earth Program :Special Colloquium 2

1-1-0

 

Autumn

 

COE Earth Program :Special Colloquium 3

1-1-0

 

Spring

 

COE Earth Program :Special Colloquium 4

1-1-0

 

Autumn

 

COE Earth Program :Special Colloquium 5

1-1-0

 

Spring

 

COE Earth Program :Special Colloquium 6

1-1-0

 

Autumn

 

Chemistry of the oxygen atmosphere

1-0-0

Maruyama, et al.

Autumn

 

Science of Photosynthetic Organisms

1-0-0

Maruyama ,Ohta

Spring

 

History of life and modern life under extreme environments

1-0-0

Maruyama ,Kohshima

Spring

 

Project Managing Skills ‡T

2-0-0

Kadota

Spring

 

Project Managing Skills ‡W

2-0-0

Furuta

Autumn

 

Advanced Course in Bioengineering I

1-0-0

 

Spring

O

Advanced Course in Bioengineering II

1-0-0

Kinoshita

Spring

E

Advanced Course in Bioengineering III

1-0-0

 

Autumn

O

Advanced Course in Bioengineering IV

1-0-0

 

Autumn

E

Advanced Experiments of Bioscience and Biotechnology I

0-0-2

 

Spring

Master's Course ‡@

Advanced Experiments of Bioscience and Biotechnology II

0-0-2

 

Autumn

Master's Course ‡@

Seminar in Bioengineering I

1

 

Spring

Master's Course ‡@

Seminar in Bioengineering II

1

 

Autumn

Master's Course ‡@

Seminar in Bioengineering III

1

 

Spring

Master's Course ‡A

Seminar in Bioengineering IV

1

 

Autumn

Master's Course ‡A

Seminar in Bioengineering V

1

 

Spring

Doctoral Course ‡@

Seminar in Bioengineering VI

1

 

Autumn

Doctoral Course ‡@

Seminar in Bioengineering VII

1

 

Spring

Doctoral Course ‡A

Seminar in Bioengineering VIII

1

 

Autumn

Doctoral Course ‡A

Seminar in Bioengineering IX

1

 

Spring

Doctoral Course ‡B

Seminar in Bioengineering X

1

 

Autumn

Doctoral Course ‡B

Advanced Biology

2-0-0

Chujyo

Spring

Tsinghua University

Advanced Biochemistry

2-0-0

Wang

Spring

Tsinghua University

Advanced Structural Biology

2-0-0

Takenaka

Spring

Tsinghua University

Molecular Recognition on Biomolecules

2-0-0

Kudo

Spring

Tsinghua University

Advanced Bioorganic Chemistry

2-0-0

Chujyo

Spring

Tsinghua University

Advanced Molecular Biology

2-0-0

Wang

Spring

Tsinghua University

Advanced Biofunctional Materials

2-0-0

Akaike

Spring

Tsinghua University

Bioengineering Now

2-0-0

 

Spring

Tsinghua University

 

 

 Department of Biomolecular Engineering

 

Class

Credit

Lecturer

Semester

Note

Bio-intern Ship I

0-0-2

Ohta et al.

 

Spring

C

Bio-intern Ship II

0-0-2

Ohta et al.

Spring

C

Bioinformatics

2-0-0

Tabata et al.

Spring

C

Industrial Sociology

2-0-0

Nureki et al.

Spring

C

Brain Science

2-0-0

Matsui et al.

Spring

C

Biotechnical Reading

2-0-0

Shibata

Spring

C

Measurement of Biomolecules

2-0-0

Fujihira

Spring

E

Advanced Physical Chemistry of Biomolecules

2-0-0

Inoue

Autumn

E

Biological Computational Chemistry

2-0-0

Sakurai

Spring

O

Biophysical Chemistry

2-0-0

Ohtani

Spring

O

Biomimetic Chemistry

2-0-0

Okahata, Mori

Spring

O

Artificial Bioorganic Chemistry

2-0-0

Mori, Okahata

Spring

E

Advanced Biofunctional Materials

2-0-0

Akaike

Autumn

E

Biofunctional Molecule Design

2-0-0

Akaike, et al.

Spring

O

Genome-based Drug Discovery

2-0-0

Ishikawa

Spring

E

Molecular Design of Biological Importance

2-0-0

Urabe

Spring

E

Asymmetric Synthesis

2-0-0

Kobayashi

Autumn

O

Chemistry of the oxygen atmosphere

1-0-0

Maruyama, et al.

Autumn

 

Science of Photosynthetic Organisms

1-0-0

Maruyama, Ohta

Spring

 

History of life and modern life under extreme environments

1-0-0

Maruyama, Kohshima

Spring

 

Project Managing Skills I

2-0-0

Kadota

Spring

 

Project Managing Skills IV

2-0-0

Furuta

Autumn

 

Advanced Course in Biomolecular Engineering I

1-0-0

Fujita

Spring

O

Advanced Course in Biomolecular Engineering II

1-0-0

 

Spring

E

Advanced Course in Biomolecular Engineering III

1-0-0

 

Autumn

O

Advanced Course in Biomolecular Engineering IV

1-0-0

 

Autumn

E

Advanced Experiments of Bioscience and Biotechnology I

0-0-2

Suga, et al.

Spring

Master's Course ‡@

Advanced Experiments of Bioscience and Biotechnology II

0-0-2

Suga, et al.

Autumn

Master's Course ‡@

Seminar in Biomolecular Engineering I

1

 

Spring

Master's Course ‡@

Seminar in Biomolecular Engineering II

1

 

Autumn

Master's Course ‡@

Seminar in Biomolecular Engineering III

1

 

Spring

Master's Course ‡A

Seminar in Biomolecular Engineering IV

1

 

Autumn

Master's Course ‡A

Seminar in Biomolecular Engineering V

1

 

Spring

Doctoral Course ‡@

Seminar in Biomolecular Engineering VI

1

 

Autumn

Doctoral Course ‡@

Seminar in Biomolecular Engineering VII

1

 

Spring

Doctoral Course ‡A

Seminar in Biomolecular Engineering VIII

1

 

Autumn

Doctoral Course ‡A

Seminar in Biomolecular Engineering VIIII

1

 

Spring

Doctoral Course ‡B

Seminar in Biomolecular Engineering X

1

 

Autumn

Doctoral Course ‡B

Advanced Biology

2-0-0

Chujyo

Spring

Tsinghua University

Advanced Biochemistry

2-0-0

Wang

Spring

Tsinghua University

Advanced Structural Biology

2-0-0

Takenaka

Spring

Tsinghua University

Molecular Recognition on Biomolecules

2-0-0

Kudo

Spring

Tsinghua University

Advanced Bioorganic Chemistry

2-0-0

Chujyo

Spring

Tsinghua University

Advanced Molecular Biology

2-0-0

Wang

Spring

Tsinghua University

Advanced Biofunctional Materials

2-0-0

Akaike

Spring

Tsinghua University

Bioengineering Now

2-0-0

 

Spring

Tsinghua University