♦ International Course in Bioscience and Biotechnology Program Tokyo Institute of Technology
1. Program Outline
Integrated doctoral program (3 - 5 yrs)
The Graduate School of Bioscience and Biotechnology has launched a new program entitled “International Course in Bioscience and Biotechnology” within our Integrated Doctoral Education Program. The primary aim of the course is to foster student excellence within our various and sophisticated educational programs by exposing students to the advanced science and technology that underpins medical and environmental industries and to other related areas of bioscience and biotechnology. By enhanced exchange between international and Japanese students, we will produce high level researchers and engineers who will flourish as national and global leaders.
2. Course Outlines and Faculty
Graduate School of Bioscience & Biotechnology
Dept. of Life Science
Dept. of Biological Sciences
Dept. of Biological Information
Dept. of Bioengineering
Dept. of Biomolecular Engineering
3. Guide to Study in the International Graduate Course (IGC)
The program will commence in October of each year, and student education will be conducted in English. A student must obtain a master’s degree of own department in the first two years and then can graduate this course at the earliest 3 years.
4. Graduation Requirements
[Master’s degree]
(1) A student must acquire 30 or more credits in the Research Courses, the Courses by Departments and the Liberal arts and general education(G). (Listed below)
- A student must take one credit of IGC Seminar (I-IV) of own department in the Research courses in each semester. *compulsory
- A student must acquire 12 credits or more from own Departmental Courses.
- A student must acquire 2 credits of Directed Collaboration Works. *compulsory
- A student must acquire 2 credits or more from the Courses in other departments.
- A student must acquire 2 credits or more from the Liberal Arts and General Education.
(2) After acquiring 30 credits, a student usually files for a masterfs degree in the first two years. Then she/he submits a master thesis and takes the final examination and evaluation of his/her thesis.
(3) Students who are admitted to obtain a masterfs degree must take the qualifying examination for the doctoral course immediately, and those who pass it will become students of the doctoral course.
[Doctoral degree]
For a Doctoral degree, a doctoral candidate must satisfy the following requirements
(1) A student must acquire more than 4 credits of IGC Bio-Internship. IGC Bio-Internship: a 3-6 month project at research institutes or corporations in Japan. *compulsory
(2) A student must take one credit of IGC Seminar (V-X) of own department in the Research courses in each semester. *compulsory
(3) A student must present satisfactory mid-term progress reports once per year.
(4) The candidate must complete and submit a thesis for the degree, and take the final oral examination and evaluation of his/her thesis.
The candidate who satisfies the above requirements and passes the final examination is awarded a Doctoral degree.
Standard Courses
Ex.1
| 1st year |
2nd year |
3rd year |
4th year |
| M1 |
M2 |
D1 |
D2 |
| |
QP |
QP |
FP, FE |
Ex.2
| 1st year |
2nd year |
3rd year |
4th year |
| M1 |
D1 |
D2 |
D3 |
| QP |
QP |
QP |
FP, FE |
QP: qualifying presentation, FP: final presentation, FE: final examination
4. Tables of Course Subjects
| Research Courses of each department (compulsory) |
Course
Number |
Course |
Credit |
Chair |
Semester |
Remarks |
| |
IGC Seminar I (each dept) |
1 |
Mentor |
Autumn |
MC 1st year |
| |
IGC Seminar II (each dept) |
1 |
Mentor |
Spring |
MC 1st year |
| |
IGC Seminar III (each dept) |
1 |
Mentor |
Autumn |
MC 2nd year |
| |
IGC Seminar IV (each dept) |
1 |
Mentor |
Spring |
MC 2nd year |
| |
IGC Seminar V (each dept) |
1 |
Mentor |
Autumn |
DC 1st year |
| |
IGC Seminar VI (each dept) |
1 |
Mentor |
Spring |
DC 1st year |
| |
IGC Seminar VII (each dept) |
1 |
Mentor |
Autumn |
DC 2nd year |
| |
IGC Seminar VIII (each dept) |
1 |
Mentor |
Spring |
DC 2nd year |
| |
IGC Seminar IX (each dept) |
1 |
Mentor |
Autumn |
DC 3rd year |
| |
IGC Seminar X (each dept) |
1 |
Mentor |
Spring |
DC 3rd year |
Courses by Departments (in this list given in English) |
Course
Number |
Course |
Credit |
Chair |
Semester |
Remarks |
| 78023 |
Bioengineering Now |
2-0-0 |
Nakamura et al. |
Autumn |
E, C |
| 78014 |
Advanced Bioorganic Chemistry |
2-0-0 |
Urabe et al. |
Autumn |
E, C |
| 78015 |
Advanced Molecular Biology |
2-0-0 |
Kudo et al. |
Autumn |
E, C |
| 81006 |
Advanced Course of Molecular Developmental Biology |
2-0-0 |
Tanaka |
Autumn |
E |
| 81002 |
Advanced Cell Biochemistry |
2-0-0 |
Komada |
Spring |
E |
| 78021 |
Advanced Biochemistry |
2-0-0 |
Kondoh et al. |
Autumn |
O, C |
| 78022 |
Advanced Biology |
2-0-0 |
Kawakami et al. |
Autumn |
O, C |
| 78013 |
Advanced Biophysical Chemistry |
2-0-0 |
Sakurai et al. |
Autumn |
O, C |
| 78024 |
Advanced Bioscience and Biotechnology Frontiers |
2-0-0 |
Saito |
Autumn |
O, C |
| 78008 |
Molecular Recognition of Biomolecules |
2-0-0 |
Seio,Yuasa |
Autumn |
O |
| 79008 |
Biofunctional Molecule Design |
2-0-0 |
Tagawa |
Spring |
O |
| 79009 |
Advanced Life Science and Nanomedicine |
2-0-0 |
Kondoh |
Spring |
E |
| |
Natural Product Chemistry |
2-0-0 |
Kobayashi |
Autumn |
O |
| 78001 |
Advanced Course of Biological Molecular Function |
2-0-0 |
Aizawa |
Spring |
O |
| 72006 |
Advanced Developmental Genetics |
2-0-0 |
Kawakami |
Spring |
O |
| 78103 |
Structure and Function of Biological Supramolecules |
2-0-0 |
Arisaka |
Spring |
O |
| 82003 |
Advanced Course of Bioorganic Engineering |
2-0-0 |
Mihara, Matsuda |
Autumn |
E |
| 78124 |
Essential Biological Sciences |
2-0-0 |
Tokunaga et al |
Autumn |
O,C |
| 78083 |
Evaluation in International Perspective |
2-0-0 |
Sato |
Autumn |
|
| 81014 |
Advanced Course of Bioscience Communication |
2-0-0 |
Arimura |
Autumn |
C |
| 78090 |
Presentation Skill for Science and Technology |
2-0-0 |
Meldrum,Kaz |
Spring |
O,C |
| 78091 |
IGC Bio-Internship I |
0-4-0 |
Kajiwara et al. |
Autumn |
 (DC) |
| 78092 |
IGC Bio-Internship II |
0-4-0 |
Kajiwara et al. |
Spring |
| 78071 |
Directed Collaboration Works |
2-0-0 |
Kajiwara Mihara |
Autumn |
C, |
| |
Directed Laboratory Works I (each dept) |
0-0-2 |
Mentor |
Spring |
|
| |
Directed Laboratory Works II (each dept) |
0-0-2 |
Mentor |
Autumn |
|
“E” or “O” in the remarks column shows that those classes are open in even or odd year, respectively.
The courses without such symbols are open every year.
“C” in the remarks column indicates the class is common to all departments.
Taking one of these credits is compulsory. Compulsory
|
Liberal Arts and General Education(G)
|
International Communication(G)
Interdisciplinary Courses(G)
Interdepartmental Courses(G)
Arts and Humanities(G)
Career Development Courses(G)
Courses for Developing Creativity(G)
Courses for International Students(G)
|
Remarks
Refer to P.337 and P.340
|
5. Syllabus of Courses
78023
Bioengineering Now
Autumn Semester (2-0-0) (Even Years)
Prof. Satoshi NAKAMURA, Prof. Hisakazu MIHARA and Assoc. Prof. Toshiaki FUKUI
(Aim)
Most advanced research status of bioengineering is to be learned, where bio-functions derived from biological elements such as viruses/phages, enzymes, microbes, plant/animal cells are applied to the construction of innovative systems for producing materials and/or energy, and contributing environmental technology.
78014
Advanced Bioorganic Chemistry
Autumn Semester (2-0-0) (Even Years)
Prof. Hirokazu URABE, Prof. Yuichi KOBAYASHI and Assoc. Prof. Toshiaki MORII
(Aim)
Bioorganic chemistry related to “Bio activity” as well as advanced organic chemistry necessary for the study of Bioscience and biotechnology is expounded.
78015
Advanced Molecular Biology
Autumn Semester (2-0-0) (Even Years)
Prof. Akira KUDO, Prof. Hiroshi IWASAKI and Prof. Takehiko ITOH
This course will feature the molecular biological aspects of a variety of biological phenomena, such as embryogenesis, cell proliferation, cell differentiation, signal transduction, transcriptional regulation, cell response, etc. In addition, future aspects of gene technology, genetic diagnosis, and therapy will be presented.This course will be made in English.
81006
Advanced Course of Molecular Developmental Biology
Autumn Semester (2-0-0)(Even Years)
Assoc. Prof. Mikiko TANAKA
(Aim)
This course is designed to provide a basic understanding of the cellular and molecular mechanisms that regulate vertebrate development.
(Schedule)
- Introduction to Developmental Biology
- Nervous System
- Neural Crest Cells
- Heart
- Paraxial and Intermediate mesoderm
- Endoderm
- Limb Development
- Blood Vessels and Blood Cells
- Germ Line
- Regeneration
- Medical Implications
(How to Grade)
Attendance and presentation
81002
Advanced Cell Biochemistry
Spring Semester (2-0-0) (Even Years)
Assoc. Prof. Masayuki KOMADA
(Aim)
Each intracellular organelle contains specific proteins to fulfill its own function. Therefore, precise transport of proteins to destined organelles is essential for cellular functions. This course focuses on molecular mechanisms of various protein transport processes within eukaryotic cells, in relation to the functions of organelles involved. Physiological and pathological roles of the transport processes will also be a major focus of this course. Equal efforts will be made to address the fundamentals and recent findings on each subject.
(Schedule)
- Overview of organelles and intracellular protein transport
- Transport from cytoplasm to nucleus
- Transport from cytoplasm to mitochondria
- Endocytosis (transport from plasma membrane to endosome)
- Transport from endosome to lysosome
- Transport from from Golgi to endosome
- Transport from endoplasmic reticulum (ER) to Golgi
- Exocytosis (transport from Golgi to plasma membrane)
- Autophagy (transport from cytoplasm to lysosome)
etc.
(How to Grade)
Small tests in the last ~15 min of each class and a term report
78021
Advanced Biochemistry (2-0-0)
Autumn Semester (2-0-0)(Odd Years)
Prof.Shinae KONDOH, Prof.Hdeki TAGUCHI, Assoc.Prof.Yoh-ichi TAGAWA
This course will be given in English. Major areas of contemporary biochemistry will be covered to help students understand the latest progress in life science, especially from the viewpoint of molecular structures, functions and interactions with other molecules. The instructors adopt their own specialities as the topics for this course.
78022
Advanced Biology
Autumn Semester (2-0-0)(Odd Years)
Assoc.Prof.Atsushi KAWAKAMI, Assoc.Prof.Nobuhiro NAKAMURA, Assoc.Prof.Masaki KAJIKAWA
This course will be given in English. Major areas of contemporary biology will be covered
to help understand the modern biology. The themes include (1) Molecular, (2) Developmental
Biology, and (3) Molecular Phylogeny.
78013
Advanced Biophysical Chemistry
Autumn Semester (2-0-0)(Odd Years)
Prof.Minoru SAKURAI, Assoc.Prof.Toshiya OSADA, Assoc.Prof.Hiroyuki OHTANI
This lecture will be given in English. Topics on advanced biophysical chemistry will be
stated with the principles of the basic analytical instruments for the biological material.
78024
Advanced Bioscience and Biotechnology Frontiers
Autumn Semester (2-0-0)
Lecturer , Yuji SAITO
We would try to understand how important to understand basic physiology and biochemistry of a disease to develop effective drugs. We will study about diabetes mellitus and its new drugs.
78008
Molecular Recognition of Biomolecules
Autumn Semester (2-0-0)(Odd Years)
Assoc. Prof. Koji SEIO , Prof. Hideya YUASA
Principles and mechanisms of molecular recognition of biologically important molecules such as nucleic acids, sugars, proteins and small organic drugs will be discussed from the view points of organic chemistry and physical chemistry. This lecture is held in English.
79008
Biofunctional Molecule Design
Spring Semester (2-0-0)(Odd Years)
Assoc. Prof. Yoh-ichi TAGAWA
This lecture will introduce some topics on advanced biofunctional molecule design based on principles of protein engineering and biomaterials. As examples of biofunctional molecules, cytokines and antibodies will be focused.
79009
Advanced Life Science and Nanomedicine
Spring Semester (2-0-0)(Even Years)
Prof. Shinae KONDOH
It aims to obtain the rudimentary knowledge of life sciences, and to understand the latest studies related to an advanced medical treatment that applies nanotechnology, the cellular engineering, molecular biology, and the genetic engineering.
Natural Product Chemistry
Autumn Semester (2-0-0)(Odd Years)
Prof. Yuichi KOBAYASHI
78001
Advanced Course of Biological Molecular Function
Spring Semester (2-0-0)(Odd Years)
Assoc. Prof. Yasunori AIZAWA
This course is designed for students interested in understanding eukaryotic gene expression on a genomewide scale. Topics include genome structures and function, RNA processing, mRNA translation, classical and recently discovered noncoding RNAs, and RNA-based technology. Focuses upon maior concepts and recent advances in mammalian genomics and transcriptome.
72006
Advanced Developmental Genetics
Spring Semester (2-0-0)(Odd Years)
Assoc. Prof. Atsushi KAWAKAMI
(Aim)
Cellular and molecular mechanisms that regulate animal development, organ formation and related issues will be studied. Through the studies of developmental genetics and related areas, students will develop ability for oral presentation in English about respective researches and/or issues related to developmental genetics. Final goal of this class is to cultivate a faculty for logical thinking and scientific communication.
(Schedule)
1. Introduction, schedules etc.
2. Developmental genetics in model animal, particularly in small fish species
3. Cellular and molecular background of tissue regeneration
4-12. Presentations by students
(How to Grade)
Attendance and presentation
78103
Structure and Function of Biological Supramolecules
Spring Semester (2-0-0)(Odd Years)
Prof. Fumio ARISAKA
Many proteins acquire specific functions by assembling into supramolecules. In this lecture, bacteriophage will be chosen as an example of a supramolecule and will be discussed from the viewpoint of supramolecular structure and assembly. After reviewing the structure and assembly mechanism of bacteriophage particles, methods to elucidate the mechanism of assembly will be explained.
82003
Advanced Course of Bioorganic Engineering
Autumn Semester (2-0-0)(Even Years)
Prof. Hisakazu MIHARA, Assoc. Prof. Tomoko MATSUDA
In a half of the lectures, basic and advanced research status of biocatalysis is to be learned. The other half is regarding chemical syntheses of biomolecules, DNA &peptide, and those applications in biotechnology.
78124
Essential Biological Sciences
Autumn Semester (2-0-0)
Prof. Makio TOKUNAGA, Prof. Susumu KAJIWARA Prof. Shinae KONDOH, Assoc. Prof. Mikiko TANAKA
The aim of this class is to get the basic knowledge of biological sciences for the graduate students who start to study about biology and biotechnology. The essences of biochemistry, biology, biophysics, molecular biology, and cellular biology for understanding of advanced bio-researches are lectured in this class.
78083
Evaluation in International Perspective
Autumn Semester (2-0-0)
Assoc. Prof. Yuriko SATO
Evaluation is a useful tool for management and self-advancement. By taking this course, students are expected to deepen their understanding of major evaluation theories, their historical background and application in the field of international cooperation and science & technology from international perspective. They can also expect to acquire basic evaluation skills through performing evaluation of their chosen topics or meta-evaluation of the existing evaluation reports.
81014
Advanced Course of Bioscience Communication
Autumn Semester (2-0-0)
Lecturer, Naomi ARIMURA
Naomi Arimura is an English woman, involved in the class of English communication. In this class, English conversation is mainly performed backuped by video making and debate in English.
78090
Presentation Skill for Science and Technology
Spring Semester (2-0-0)
Assoc. Prof. Martin MELDRUM, Lecturer, Diana Marie KAZ
The science-based English teacher teaches the presentation skill concerning the science and technology. It aims to learn various techniques to explain own research & development to others, to discuss with others and to debate as others etc., and to foster ability of English presentation.
78091
IGC Bio-Internship I
Autumn Semester (0-4-0)
Prof. Susumu KAJIWARA et al.
This class is a practical project at research institutes or corporations in Japan from three to six months.
A student must take this class or IGC Bio-Internship II.
78092
IGC Bio-Internship II
Spring Semester (0-4-0)
Prof. Susumu KAJIWARA et al.
This class is a practical project at research institutes or corporations in Japan from three to six months.
A student must take this class or IGC Bio-Internship I.
78071
Directed Collaboration Works
Autumn Semester (2-0-0)
Prof. Susumu KAJIWARA, Prof. Hisakazu MIHARA
To foster the creativity and planning about research and development in bioscience and biotechnology fields, and the scientific communication with the students from the other countries, the international graduate students plan to develop a new bio-industrial product(goods) with a team (2-3 students).